Tuesday, February 16, 2021

Self-application of my research




Believe it or not, David Sinclair is 50 and professor of medicine at Harvard. Based on him

https://aaqg-arunarya.blogspot.com/2021/02/paradigm-changer.html

Don't forget to chase links. It is a huge number of essays linked together. I expect comments making a lot of work free for you!


Self-application and your (reader) applications

Aging - I grow old, weak, frail and disease ridden. There is nothing doable by my immediate family or was by me or medical professionals when my father died. Last years were hard on him, he lived on to 88, but one day he died while we took him to the emergency. A finite life, longer than normal, with no long debilitation at the end is what I can promise to myself, even if any further improvements are in the future. The method I design is open for a specialist to recreate, right now there is no tested method, and my family has refused to trust my medical knowledge, the best I have is a commitment to follow me after my experience at age loss and more important, freedom to screw myself.

Relief from diseases

I have the following diseases with no real fix in allopathy, even though allopathic help will be sought by me on events. These are

1. Diabetes

2. Heart diseases

3. Essential tremor

4 Aging

Aging solution is certain to solve others. Heart was caused third by smoking (Quit 39 years ago), third by diabetes and third by genetics. Diabetes in full genetic, as is essential tremors. Cause is irrelevant. I have four diseases from genes and time. The source is important to decide what kind of intervention, if any, is best. There is precisely one that will certainly defeat all, reducing the biological age of cells involved in each. But there are no off-the-shelf subset mechanisms in biology or chemistry. The aav techniques (adeno-associated virus), that selectively direct a medicine to an activated subset, or RNA technology boosted with applications in rapid vaccine development for Covid-19, do not constitute a solution for non-specialist like me.

For blood aging there are two broad schools of thought: one in which there are regenerative factors in young blood that can be isolated, and another in which aged blood contains regenerative factors that cannot function due to an oversupply of pro-aging factors. I am in the latter camp.

A general age reduction will automatically benefit diseases. So in effect, only solution to aging will work on all. I expect 20 year reduction, which puts me just before diabetes or heart. Great if it works, has not for anyone (unless try anonymously), and requires 10 years from aping Dr. Sinclair (he shows 15) and 10 years from mice experiments at UCB (mice do lot better than10 years, percent wise, Grifol safety data) and mechanism independence (looks so). So the method I will do to self is safe (vitamin B3 chemicals and plasma update) and efficacy (liver damage control, conservative Mice prediction). Results are for me, worst case nothing exciting happens. They will Yamanaka factors medicine within 10 years (my prediction). Looks like Plasma update can be done a few times.

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