Thursday, January 27, 2022

Exosome for Aging

 


Exosome (vesicle)

FunRich: An open-access standalone functional enrichment and interaction network analysis tool


Dr. Sinclair can make sense of this and send it to better-known targets. E5 works, based on believed Dr. Horvath. It seems to contradict parabiosis correction by Drs. Conboy. What goes?

Dr. Katcher has obligations to his funders without lying. I assume he did that by using young blood in E5. Youngblood is not needed and total confusion for all he wishes to not compete! But then why does E5 work? The answer is very obvious for the main past work of Dr. Katcher- finding the betterment of cancer! 

For success, he needs to know how metastasis happens ie through exosomes. Exosomes are hard to detect as very small. But why did Drs. Conboy fix elders without young blood? Aging comes in parts. The Conboy use of only albumin has limits and is probably not repeatable. Why does E5 work? Because it uses exosomes. Dr. Katcher knows them well as a biology teacher. These work between distant cells. All kinds of distant cells can be recruited to build the needed proteins. This is done by putting mRNA required for the resultant protein. These are put in exosomes along with source-id protein to penetrate the target. Distant cells present the mRNA to nucleolus bound DNA and make the protein. Note that some source protein in the exosome enables the entry of mRNA.

Generic proteins can be used in E5 for proteins desired. These can not be exotic for E5. E5 is for rats. Corresponding for humans is easy to select by a biology teacher.

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