Summary 2022
My colleagues and their loved ones continue to die, no one has reported, despite their attempts to apply state-of-the-art technology. Must mean one or more of
1. Unfamiliarity with the modern science of aging
2. Knowledge but conscious decision to escape probably useless expenses
3. Lack of belief due to some kind of fatalism, luck, religion, etc.
About #3, everyone has the right to be stupid, except that our civilization will advance to a state where such idiots will be held accountable for murder. The same applies to greedy #2. The people at no. #1 will be charged with negligent homicide, exactly like the driver involved in the accident.
The only defense tolerated is that I tried this way (from a top scientist) after reading and still failed.
Who are these outstanding scientists and why?
Any person who argues something that is not empirical is a meta-moron. Everyone on the top list did Nobel-quality work (recognized in the senior community by the overwhelming majority) and then turned in another such piece of research.
There are only a few, found by continuous work of 20 years.
All upper field of Aging
1. Dr. de Grey, for presenting/developing an engineering approach to the problem of aging and senolytics
2. Dr. Sinclair, for NMN and Theory of Aging 2019
3. Dr. Yamanaka for inventing the Yamanaka factors and iPSC.
4. Dr. Horvath for mDNA/GrimAge and the applicability of methylation in Eutherian
5. Drs. Conboys for early heterochronic parabiosis and not young blood but simple albumin works
6. Dr. Greg Fahy for TRIIM and TRIIM-X
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After identifying some of the best doctors, the next question that arises is the value added by me, a doctorate or a doctor. After reading through independent systems, any intelligent patient will ask questions that have also arisen in me and which I have intelligently answered.
1. What is my goal? Why do I consider the set of identified as de-aging 1.0?
I divide aging into stop/slow down and restart. There is a lack of acceptable quality testing for any of the identified methods to have a reliable reset.
De-aging 2.0 occurs when age reversal becomes reliable. Until then, delaying aging is insufficient. Anecdotal evidence suggests that the identified methods could be developed for a reliable reboot, but I don't think so. This is because they are all different from the Yamanaka factors being researched and will likely result in a usable protocol and chemicals within 5-20 years. The goal is to somehow live up to the 1.0-singularity that will be built around the Yamanaka factors.
2. Dr. Yamanaka converted (induced) any cell by applying Yamanaka's OSKM factors into new master cells capable of becoming any cell, i.e. converted to iPSC cells. The magic happens as the same factors do with any Eutheria animal and beyond. This suggests the correctness of evolution. Other magic happens from the 1928 research that grew a normal frog from denucleated frog masters with the usual aged frog nucleus! Genetic information is somehow preserved, which is possible with the epigenome somehow turning genes off and on depending on the shape of the cell (hair, skin, bone, organ, brain, etc.). Another strong suggestion comes from the fact that no child is born old, regardless of the age of the mother and father, human or animal!
One notable magic in nature is that Yamanaka factors are capable of being taken as a medicine in pulses of short duration by living humans. Going back to multi-cell iPSCs gives you cancer, but pulsed use maintains specialization but reduces age! That suggests to me that age reversal is feasible and feasible within the next 20 years. And one can live at least 20, more likely 100 years, using the identified technologies.
3. Let me keep my scholarship. This means that there are no statements about the safety, security, and effectiveness of the unit. Doctors should be replaced by companies that provide indefinite life. However, methods are discussed from the point of view of intake method (drug administration), composition, bioavailability, chemical sources, dosage, and purity. These seem obvious, but they are not, and they apply to medicine for all diseases, including supplements and foods. Drugs are not like products. They cannot be composed blindly. The delivery method is crucial.
it is absolutely important. Sellers' quality judgments require experience. The doses require experience in results.
4. composition
We describe the recommendations by defined words, using the name of the main known initiator (regardless of derogatory source research).
A. Dr. Sinclair and NAD+ boosting
B. Dr. de Gray and senolytics
C. Dr. Kennedy and AKG
D. HEALTH boosters D3/K2 and Hyaluronic Acid
E. Dr. Fahy and IGF-1/DHEA
I wait and look at C60/oleic acid and E5.
The following document describes everything. The five methods above seem independent and composable.
5. Who is right?
The main question in the mind of a consumer, faced with conflicting information, is always who is right. Even if one starts out normal, all the smart ones become cynical from a little experience. I know that my statement should surprise many! I submit that it depends on how quickly you want answers: quickly if the recommender also applies recommendations to itself in a transparent way (unlike diseases, aging affects us all). The longest term is FDA.
6. Method of drug administration and bioavailability
Both are different, but the same for liposomes, while about as slow as dust, liposomes provide high dissolving ability, protect the drug from the stomach and liver, for intact blood delivery, and easy entry to the cells because the skin of the so-called is like the skin of the liposomes. There is no cell group address unless it is pre-built into the skin of the lipo, so liposome injection is used for delivery, but it uses a doctor to administer, which is difficult for a supplement. Unlike a disease, the target can be any cell, and the only direction is needed for efficient and uniform application.
7. Product purity
Purity in the US is food grade (97%) and pharmaceutical grade (99%). Contaminants cannot be contradictory. Since the administration of the market is essentially decentralized, a similar system is legally needed. A typical confusion is the work of the court. Most of the drugs I use are liposomes, so the pharmaceutical grade is needed anyway.
8. Dosage, Sellers, Period, verification, monitoring, feedback, others
Attached here is a list of doctors selected for a follow-up of patients, not self-taught. They will perform Dosage, Vendors, Period, Check, Monitoring, Feedback, others based on our database that will reflect provincial, national, and international EXPERIENCE.
I consider myself super competent, but I pass my list to my doctor, Dr. Neeti MD, and I accept and carry out her orders.
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