Liposome

 

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My essay on cell medicine as distinct from Allopathy and more dealing with senescent cells for cancers and aging gave me a tremendous boost to understand liposome. It is worth knowing and doing to increment massively the powers of vitamins and age improving NAD+ supplements. I am sure you know nothing about it. It is a manifold of many many hollow phospholipids, each appropriate for coating some medicine in a phospholipid layer and the coat is used for many things including targeting, protection (stomach acid and liver), improving (by a lot) the bio availability, reduced toxicity and increased permeability across membranes etc. The material can be bought separately, or in some cases made at home. I now do have a calling beyond cell medicine, really included in it, to encourage buy only liposomal medicine or do the procedure at home with simple mixie type machines and espresso coffee maker. Liposome is somewhat new,  1964. It has taken 57 years to today's applications, major recent success in the USA of kitchen making. The only block in Universal application is ignorance.

Intuitively, the idea is to milkify powders. Milk is like an impossible solution of oil and water in the cheese liposome. This mixing gives tremendous power to cream (to fatten). It is really sandwiching insolvent into solvent by constructing a phospholipid layers by two surfaces - a hydrophilic and a hydrophobic bilayer and inserting nanoparticles of insoluble, the whole is then soluble. Within the human body, the medicine is protected from stomach acid and liver but easily bared in right internal tissue which digests the layers. It is a good way to eat insoluble vitamins, glutathiones, aging chemicals like NMN or NR etc. It looks like nanoparticle technology is needed, but that can be achieved easily.

Phospholipids, also known as phosphatides, are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group, and two hydrophobic "tails" derived from fatty acids, joined by a glycerol molecule. Marine phospholipids typically have choline, ethanolamine or serine. Phospholipids are a key component of all cell membranes. The phospholipids are amphiphilic. The hydrophilic end usually contains a negatively charged phosphate group, and the hydrophobic end usually consists of two "tails" that are long fatty acid residues.

Milk exists despite what it is – a suspension of oil (ghee) in water, not normally possible but possible due to cheese part of milk, which acts like a liposome. Now think of suspension of a non-bio available molecule like a vitamin which does not mix well with water as K2 or NMN. Even bigger, like Glutathione. While not bio available in powder form, it will be easily up to 100 times more available in liposome form! Such a material is difficult to survive extended periods in a shop, but the liposome former can be sold separate and special mixie like churning can create an acceptable liposomal variant at home. People don’t, but can in a method I will launch to make liposomal vitamins and drugs at home. Why pay 30-100% increase in cost for a product with suspect goodness. IN A LIPOSOMAL NMN IN AMAZON USA PAGE. MANY CUSTOMERS WERE WORRIED THAT SOME TIMES WHAT THEY BOUGHT WAS CLOUDY, SOME PRODUCTS WERE CLEAR AND SOME CHANGED IN DIFFERENT SAMPLES OF SAME BOTTLE. Helps to understand Liposome semantically! Best form Liposomal form at home to prevent precipitation over time.

What is needed? A utensil and commercially sold liposome precursors like LipoSorb. The utensil is a vacuum driven mixie like. The idea is to use regular mixie for 5 minutes and the advanced for about the same time. Consume liposomal form in a day to, often within a weak. You can get more homie by making own liposomal media from milk!

WHAT IS YOUR INTEREST?

1. Never have I seen a technology, new and experimented in the USA, but missing  and required even more in India. There is a small hassle-factor in kitchen liposome, but the situation is like tailoring, one can buy ready-made, but the art of stitching is taught to all women and unlike the USA, THE ENTIRE GARMENT IS NOT DISCARDED after minor functional defects. Of course, one further this thread in thought and imagine all kinds of self diagnosis appliances and vehicles with a diagnostic port into which the diagnoster is inserted and that determines what to replace to get a target functionality. End of caste of mechanics in shops and workshops! In fact, one can allow internet add-on, which connects to remote mechanics for remote diagnosis, a perfect port for your car.

2. Liposome is excellent for bioavailability and protection from two enemies of all drugs - stomach acid and liver. In most cases, what matters is concentration in circulating blood. One way to get that is intravenous or correctly injected drugs. Other way is under the tongue - sub-lingual method. Third is nasal drops. Even better is Liposomal, the material faces stomach and liver in liposome shield of phospholipids that transparently dissolve in blood circulation. THE METHOD WORKS FOR ALL KIDS OF THINGS AND REQUIRES NANOPARTICLES to be surrounded by phospholipid. It is virtually impossible to do it but for high temperature draw of phospholipids drug powder doable at home with espresso coffee maker! Of course, one can freeze-dry the solution for ready-made liposomal powders! The cavity in liposome must allow one molecule of drug, and different drugs have different ideal liposome. However, somewhat bigger cavities are ok,  perfect mix-match research for, perhaps cranky dreamer, retired like me.

3. Even if I fail generally, singular successes in SUPPLEMENTS AND OTC are usable. I can safely use self body as tester, for the worst case is no different from direct ingestion! Ideal time to test psyllium is constipation and cough powders is when  coughing! Why just take drugs when science and bank balance can benefit?

 (To be continued)