2023 papers and links

Sinclair 2023 aging

2023 https://youtu.be/2jTbeyEWBIQ

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Ever believable engineering for immortality and purpose

 

First, existing humans must achieve bio-immortality through negligible senescence NS doable through non-medical chemicals derived from a deep study of evolution and derivation of all DNA elements from Yamanaka factors OSKM which can be consumed as OSK triples in interrupted form. The proof is so published in a peer-reviewed paper in nature by mice experiments of Dr. Sinclair of Harvard medical school in Boston on Jan 23, who could increase and decrease age in mice at will. Humans are next by 1925, my time estimate.

After getting bio-immortality, the job is not done yet for death can come from several other physical scientific processes operational at once, the earliest is fatal. Bio-immortality is unusual for humans but common in some animals as called NS-like lobsters, some frogs, alligators, sharks, whales, etc. There is no such thing as aging for them. Cancers are escaped by dense cells. All the long-life NS species live for 10-500 years and die from cancers, predation, etc. Rather than old-age. In fact, I believe in the programmed theory of aging.

The programmed theory of humans is a blessing in evolution because much smaller life allowed fruitful replacements to the species 10 times faster than other animals and 100 times faster than trees. Technical evolution Techev has happened in 4000 years, 100 times faster than human species separation in evolution life, hence Techev is an ignorable period in evolution history relevant to aging.

Technological evolution proceeds exponentially. It has allowed just the human animals to attack, over all other animals, cancer, negligible senescence or natural aging and cancers, and will engineer all others. Unfortunately, positive outcomes are most commonly comfortable and all increase age as mTOR, adversely affecting age-boosting all others. Eventually, all causes can be protected against by photon-achieved life and redundancy, and reanimated by cyborg download.

 Timeless travel in the universe is possible as photons, despite long distances of 10 light years between the nearest stars and millions of light years between the nearest galaxies. Only after a quadrillion years will an LGO be needed to allow multi-verse bridging. Then perhaps more than quadrillion years will be needed to explore a suitable universe in the multi-verse. Or the search can proceed with exponentially growing cyborg counts in a massively parallel style.

[...] surround links

 The original essay is just 6 links in immortality, my masterpiece which presents the first human-known immortality and a purpose of long life. These were to pieces, logically a part of the essay, but imparts to allow complete treatment of the final threads and easy determination by reader chosen order. Such treatment was not considered credible and many new links were added for reference purposes. But such a document buried essay pieces in one of many and distracted. Rejected were two color solutions to allow easy use by the color blind.

The method chosen adds a distinguishing mark. [<link>] was chosen and used, People should find a similar solution for 2 meanings to links. Different extensions are possible with a higher link distinguished by a pressed identifier before the [], as in more_text[<link>], with more_text as the default meaning on Ellison.

There can be no complication of detection even when the [] are in the non-link test as the only time the convention is used is with at least one link argument. The prefix to [] can be an identifier or any parenthesized prefix, each without trailing whitespace.

science beyond falsification

 

Most people define science as possible falsification. This is untrue as this essay shows. It is somewhat akin to the necessary modification definition of truth that is achieved by stating that correlations between processes of 5 sigmas define truth.

The future expected life of products also must be considered science. It is not enough that a seller of a product that fails its warrantee can claim failure of science as an excuse. Beyond that, consider

1. Bridges designed for a 500-year flood

2. Solar segments on a roof designed for 25-year life within 25 years under the usual climate

3. Batteries designed for a life of 150 years.

4. 1000 year era life with thymus fix that long

Common to all the examples so far is that one can define the process of future service as a valid science of estimates that is assumed to be accurate based on scientific deductions. That the service life will be similar to proven examples is only true in the scientific deduction. One can question that assumption based on sample size, etc. The belief that it will hold given an adequate sample is considered scientific deduction. The education may require failure testing in samples and partial testing of elements.

This must allow extrapolation. Extrapolation under constraints is an integral part of failure sciences that cannot be captured using falsifiability. Even potential falsifiability. What does it mean to be potential immortality, No way of testing that is possible. But an object can be defined as having truly infinite life by being repaired every time a part is damaged, even all parts at once.

Part of the entity may be information. Usual redundancy-based techniques will have to be used on total failure, but the information can be viewed as another part. Such an entity never dies. The life science here is not falsifiable, even though generalizing to potential falsifiability. 

The statement 'thymus fix leads over to the 1000-year life" is well-formed and falsifiable, as is the fact that I believe it. And one does not need needs to test it before 1000 years.

Science is falsifiable or validly extrapolationable.

Tolerable sci-fi

 

Sci-fi is fundamentally different from tech-fi in that no further facts are needed to show that the sci-fi assumed facts are achievable. They are still used in tech-fi clearly labeled as sci-fi in every instance and cannot be used as a basis for any tech-fi facts. Sci-fi facts can be counterfactual and contradictory, hence paraconsistent.

Spanish why immortality

Abstracto

 Este ensayo trata sobre la verdadera ingeniería de la inmortalidad y qué hacer en el tiempo extraído triunfalmente de la naturaleza. Independientemente de otros significados obscenos asociados obsoletos, el triunfalismo me define en la victoria sobre un supuesto axioma de la naturaleza, incluso si los que vilipendian a los EE. UU. o los ingenieros como satánicos se preocupan. La vida no es un episodio corto.

  Tres temas en cuestión son por qué buscar la inmortalidad, cómo obtenerla y el despido de otros pretendientes.

¿La desestimación de otros demandantes?

Esto es ing-fi basado en ingeniería basada en ciencia existente nunca postulada. La diferencia esencial con la ciencia ficción es la capacidad de hacer una estimación del tiempo firme en función de los desafíos a los mejores ingenieros. Todos los demás pretendientes basados en cualquier religión, espiritismo, pseudociencia, antigüedad, política, etc. fallan ante cierta inmortalidad de algo afín al alma u otras ciencias no realizadas son inútiles ya que no permiten estimaciones de tiempo significativas por parte de la mayoría de los ingenieros reconocidos existentes. La crioconservación del cuerpo es un método de ciencia ficción rechazado por fallas en las estimaciones de tiempo.

¿Cómo conseguirlo?

Básico para obtener la verdadera inmortalidad es primero derrotar el envejecimiento a la bio-inmortalidad

1. Vence el envejecimiento del ADN

2. Vence otros envejecimientos

En este punto, eres bioinmortal pero sigues siendo vulnerable a otros métodos físicos. La bio-inmortalidad no es necesariamente inusual. Se sigue de una senectud insignificante. Se ve en langostas, cocodrilos, ballenas, etc. Ninguno está a salvo de la muerte por depredación y cáncer. Estos animales finalmente mueren por depredación o cánceres, etc. Solo una especie en desarrollo tecnológico como nosotros, los humanos, puede desarrollar una cura para los cánceres y la senescencia insignificante.

La inmortalidad total solo es posible con la descarga del cerebro basada en la tecnología desarrollada por el MIT. El cerebro primero se expande a un tamaño enorme. Existe tecnología para el tránsito a un cerebro cyborg. La descarga se puede preservar contra todos los modos de destrucción, así como contra viajes atemporales entre estrellas.

3. Inmortalidad total

¿Qué hacer con eso?

La carga descendente puede estar precedida por un viaje muy acelerado dentro de nuestro sistema solar y las estrellas cercanas que utilizan el vuelo dinámico. ¡Le da significado a la vida (viajar en el universo) y eventualmente se mueve a otro objeto multiverso en la fase final de alguna manera de ciencia ficción!

4. viajar por el universo

5. tránsito de estrellas y galaxias

Nota del autor

Esta es la versión en inglés y ficción, me sorprende que, a pesar de la apariencia de ciencia ficción, no se necesita nueva ciencia, la bioinmortalidad es posible, y soy un creyente serio y lo aplico por mi cuenta. Existe una limitación conocida de NMN, a saber, una vida útil de 15 a 20 años. Sin embargo, el más aplicable y probablemente bueno para el uso repetido durante 10 000 años ya se está investigando y es probable que se use en 5 años, ya que se basa en los factores OSK Yamanaka, probablemente ampliamente disponible a un precio razonable en 7-10 años. Eso está dentro de mi vida natural, también antes de que mueran mis glóbulos blancos, mis suplementos actuales me dan vida y más, la fuerza para hacer ejercicio. Parezco 50 y parezco 50-60 cuando se hacen los factores de Yamanaka. ¡Nunca habrá necesidad de ninguna otra mezcla de suplementos de asistencia para la edad! tengo muchas ideas de unicornios

1. Software para el cifrado seguro de computadoras cuánticas, recientemente más allá de las computadoras clásicas

2. Retracción de edad única a 10-20 años para personas de 60 a 70 años

3. Crecimiento y refusión en laboratorio de glóbulos blancos para edades de 60 a 80 años

4. Experimentos de TOHB en ratones para corregir y practicar los telómeros

5. Formas de liposomas de todos los medicamentos recetados en forma de polvo

y los haré a tiempo completo ahora y gastaré dinero real, posible solo en India, con la ayuda de las SS de EE. UU.

 

Último autoenlace

Anti-envejecimiento hasta ahora: debe comprender la corrección del envejecimiento al estilo del Dr. Sinclair, esto es más

¿El problema?

El antienvejecimiento no es un tema genuino de la medicina moderna, sino un verdadero tema de ingeniería. He diseñado y utilizado en mí mismo un cóctel de suplementos. En su mayoría no son medicamentos, la FDA no tiene por qué regularme. Mi experiencia autoclínica ha descomprimido algunos reclamos haciendo agujeros en estos reclamos pero por parte de algunos médicos honestos, así como también de algunas compañías y vendedores de suplementos fraudulentos. ¿Por qué hay algunos médicos honestos en la línea? La verdadera reducción de la edad no tiene sentido si se logran los mismos efectos, incluso algo más lentos, tomando otros suplementos que tienen otros efectos positivos. ¡Estuvo bien! ¡Esto es muy controvertido, en el sentido de que los médicos honestos con pruebas clínicas garantizadas se declaran innecesarios! La esencia del método del Dr. Sinclair es que la mayoría de los métodos de fijación del envejecimiento de los venerables "Sellos distintivos del envejecimiento" se logran mediante la fijación del ADN, ¡y yo los he validado de manera diferente!

¿Contribuciones?

Basado en un extenso conocimiento biológico de dos décadas, la técnica esencial que utilizo para sortear este problema crucial es admitir solo suplementos cuyo mecanismo ha sido establecido. Si el suplemento adicional no tiene beneficios adicionales, entonces el suplemento ya no se usa a menos que un estudio posterior establezca de manera concluyente un beneficio más allá del período probado. Además, no se utilizan suplementos con productos químicos que no necesitan un catalizador, ya que es probable que interfieran con algún medicamento futuro. Esa es la razón principal para dejar caer la quertecina.

¿Extensión de qué?

El principal beneficio de la teoría del envejecimiento de la reparación epigenética del Dr. Sinclair es que la mayoría de las otras teorías pueden ignorarse porque la reparación epigenética activará caminos que repararán cualquier daño que la mayoría de las otras afirmaciones estén reparando, en el peor de los casos, una solución más lenta.

La teoría del Dr. Sinclair sobre el envejecimiento es simple y breve. El ADN humano está cubierto por material epigenético que muestra solo algunos codones que corresponden a codones activados. El resto del ADN está fuertemente enrollado. Las células pueden reparar sus roturas de ADN interrumpiendo la reproducción durante la reparación. El envejecimiento (tiempo) provoca estadísticamente fallas en la corrección de errores. Las células rotas pierden identidad e incluso causan daño de la proteína CD38 a las vecinas, eventualmente matándolas también. La vejez es fruto de este proceso progresivo de retroalimentación positiva. Hay cuatro arreglos que no se arreglan por medios epigenéticos. Estos hacen esta desviación del Dr. Sinclair, incluidas como correcciones esenciales pertinentes después de Sinclair, estrictamente elegidas por razones mecánicas, y son el soporte cerebral, el daño del mtDNA (ADN mitocondrial), la pérdida del sistema inmunológico y el acortamiento de los telómeros. Estos problemas ya han sido abordados por la literatura, incluso por idiotas que ven su solución como un completo antienvejecimiento.

¿Cómo arreglar el cerebro?

Brain fix es lo que es la psiquiatría en general. Es difícil debido a la censura de los productos químicos transportados por la sangre por la barrera hematoencefálica. También llamado uso de suplementos noootrópicos. Me limito a soluciones generalmente disponibles como soluciones equivalentes de Ayurveda por razones de costo y para pruebas adicionales de medicina no moderna, especialmente sustancias químicas cerebrales. Solo se buscan las soluciones de Ramdev por razones de confianza en la formulación y la fabricación: nunca se ha confiado ni se confiará en el Ayurveda.

La mayoría de los productos químicos son modernos con equivalentes ayurvédicos conocidos. Por ejemplo, se recomienda Bacopa Monnieri, al igual que Brahmi. El segundo esencial es Ashvagandha.

Este es un tema amplio con problemas como el Alzheimer, el Parkinson, etc., y se tratará en detalle más adelante. Otro tema es el olvido que se cree que es causado en parte por la reducción de la memoria a corto plazo.

¿Qué sucede con la pérdida de mtDNA?

La reparación del mtDNA es para aumentar la fuerza, una pérdida común con la edad. Todos los productos químicos a continuación no son necesarios. Elija un subconjunto con la ayuda de un médico. Algunos NMN ayudan.

Las correcciones de mtDNA se realizan por muchos métodos. El ADN mitocondrial (mtDNA) es distinto del ADN humano, enfrenta los desafíos universales del mantenimiento del genoma: la replicación, transmisión y preservación precisas de su integridad a lo largo de la vida del organismo. Aunque originalmente se pensó que el ADNmt se fijaba en la actividad de reparación del ADN, cuatro décadas de investigación sobre las mitocondrias han revelado múltiples vías de reparación del ADNmt, incluida la reparación por escisión de bases, la reparación de roturas de una sola hebra, la reparación de errores de emparejamiento y posiblemente la recombinación homóloga. Estas vías de reparación del mtDNA están mediadas por enzimas que tienen una actividad similar a las que operan en el núcleo y, en todos los casos identificados hasta ahora en mamíferos, están codificadas por genes nucleares.

Resveratrol o Pterostilbene - asesinos de bacterias vegetales. Todo listo recomendado.

  Shilajeet! Ayurvédico, supuestamente gran dador de fuerza.

L-Carnitina

Vitaminas B - genial de todos modos. Los uso como complejo B.

Pyrroloquinoline Quinone PQQ: aún no se ha consumido, pero se recomienda encarecidamente.

Ácido Alfa Lipoico ALA - Similar a las vitaminas, muy seguro.

Creatina - gran potenciador de la fuerza, genial con el gimnasio.

Magnesio: ¡tan útil como el calcio!

Coenzima Q10: excelente también para el corazón.

¿El sistema inmune?

Disminuye debido a la involución del Timo - significa sustitución progresiva por grasa, completa a los 60 años. Algunas respuestas inmunitarias mueren a los 80 años por la muerte de los glóbulos blancos aún vivos en el torrente sanguíneo hasta ese momento. La vida más allá del año 112 presenciado se distribuye veneno como se esperaba.

La única buena solución ahora es la vacuna siempre que se conozca la bacteria o el virus expectante. Las más conocidas son la vacuna contra la gripe y las vacunas de la serie covid. Sin embargo, todas las vacunas del sistema no logran nuevos cambios evolutivos en los patógenos y deben retomarse periódicamente.

Hay muchas soluciones anunciadas (sin comentarios) basadas en antioxidantes, que pueden ayudar (o no) a los pacientes, pero no tienen ningún efecto como las vacunas.

Tengo un nuevo método unicornio (!) derivado de células CAR T como reemplazo de glóbulos blancos cultivándolos en el laboratorio del hospital y posterior refusión, garantizado sin rechazo. En el chequeo anual de salud, sensible a todos los mayores de 60 años. Otro enfoque es a través de los métodos del Dr. Fahy.

¿Cómo arreglar los telómeros?

TOHB (Terapia de Oxígeno Hiperbárico), las aplicaciones de envejecimiento promovidas por Israel son las mejores. ¡La medicina antigua creía erróneamente que solo esto envejecía! Cada división celular reduce la longitud de los telómeros celulares en 2 años. 50-60 veces más tarde, todos los telómeros desaparecen y las células dejan de dividirse. La telomerasa aumenta la longitud y está codificada en el ADN, se produce solo en los óvulos masculinos y se descubre en todos los tipos de cáncer, lo que otorga bioinmortalidad a las células cancerosas. HBOT es útil para lesiones y miradas de cineastas, etc. Ya existen centros de servicio. Una forma patentada aumenta la longitud de los telómeros de forma similar a los buceadores profesionales. Lo considero otra startup de Unicorn en India con colaboración israelí.

Why engineering immortality

Abstract             Not so, but other competing ideas                   Latest version link

[[...] surround links] are basic to running text and are mine. Other links are references for credibility. If immortality is possible then why don't we see it? This is the babble of mentally deficient who fail to understand engineering, always working within current science to construct disruptive novel realities like los alamos, fusion, etc. It is about the existence of a limited doable estimable program.

[Negligible Senescence]

I consider it my masterpiece of 22 years of work that describes a low chance but achievable immortality, desired by humans, with a purpose, without the religious/spiritual stupidity with a nonsensical soul or any sci-fi. Never has any author in human history, found a believable engineering solution to immortality and purpose without invoking untestable facts or infinite science. As a critic, do not put your toes in your mouth by failing to click [...] links that will tell you how the header text linked is done by me.

[This essay is about the true engineering of immortality] and what to do in the time triumphally extracted from nature. Regardless of deprecated other obscene associated meanings,  triumphalism defines me in victory over one supposed axiom of nature even if by those that revile the U.S.A. or engineers as a satanic worry, saying everything has an eventual end. Life need not be a short episode.

 Three issues are how seek immortality, why get it, and dismissal of other pretenders or claimants. Even extension to 1000 years will be welcomed by my children, who can extend it some, and so on.

The Dismissal of other claimants?

Engineering, despite close association with science, trumps it for practicality. This is eng-fi based on engineering based on existing science that never postulates the end. The essential difference to sci-fi is the ability to make firm time estimates based on challenges to top engineers, a central author coined test to deal [with inadequate Popperian falsifiability].  Estimate failure improves falsifiability.

All other claimants based on any religions, spiritualism, pseudoscience, seniority, politics, etc. fail before certain immortality of something akin to the soul or other not realized sciences are useless as they do not allow meaningful time estimates by the majority of existing recognized engineers. Cryopreservation of the body is a sci-fi method rejected for the failure of any time estimates. Same reasoning destroys Jules Vern and its style passage to moon.

How to get it?

Basic to getting true immortality is first defeat aging to bio-immortality first.

1. [Defeat DNA aging]

2. [Defeat other agings]

At this point, you are bio-immortal but still vulnerable to other physical methods. Bio-immortality is not necessarily unusual. It follows from negligible senescence. It is seen in lobsters, crocodiles, whales, etc. None including humans are safe from death by predation and cancers. These animals ultimately die from predation or cancers, etc. Only a technology-developing species like us humans can achieve technology from fast evolution to develop cures for cancers, all other dangers and negligible senescence. Rejuvenation is better than deaging

Full immortality is possible only on brain download based on MIT-developed technology. The brain is first expanded to a huge size. Technology exists for transit to a cyborg's brain. The download can be preserved against all modes of destruction as well as timeless travel between stars as photons experience no time and can travel between stars redundantly.

Many techniques are much better done by printed parts stitched by AI that has associated dangers operating by itself, but I consider humans to evolve into cyborgs.

3. [Why Full immortality]

Do what with it?

The download can be preceded by vastly accelerated travel within our solar system and nearby stars using dynamic soaring. It gives meaning to life (travel in the universe) and eventually moves to another multiverse object in the final phase in some sci-fi way!

4.[ travel the universe]

5. [transit stars and galaxies]

Author note

This is an eng-fi version, it amazes me that despite the sci-fi look, no new science is needed, bio-immortality is possible, and I am a serious believer and self-apply it.  There is a known limitation of NMN, namely 15-20 years of life. However, the one more applicable and likely good for repeated use for 10,000 years is already being researched and likely to use in 5 years, being based on OSK Yamanaka factors, likely widely available at a reasonable price in 7-10 years. That is within my natural life span, also before my white cells die, my current supplements give me life and more, the strength to exercise. I look 50 and look 50-60 when Yamanaka factors are done. There will never be a need for any other age-assist supplement mix! I have many unicorn ideas

1. Software for quantum computer secure encryption, recently beyond classic computers

2. One-time age retraction to 10-20 years for age 60-70 years persons

3. White cell lab growth and re-fusion for age 60-80 years

4. HBOT experiments on mice for telomere fix and practice

5. Liposome forms of all powder form prescription medicine made by UP/India lipo-makers

and will do them full time now and spend real money, possible only in India, with USA SS help. Simple no hypocrisy means I may be wrong, unlikely as not costing money and not funded and claiming to have no reason. I do it for acknowledged support for the USA SS in my TBI, hoping that the need will vanish some day in my life. Law provides for that.

2023 anti-aging

Latest self-link [DNA aging +]

Anti-aging so far: must understand Dr. Sinclair's style aging fix, this is more. Death can come in many ways covered in my hyperfunction theory. The earliest death is enough. That you are protected from most subsequent deaths is irrelevant.

The problem?

Anti-aging is not a genuine modern medicine subject but a true engineering subject. I have designed and used on myself a cocktail of supplements. These are mostly non-medicine, FDA has no business regulating me. My self-clinical experience has decompressed some claims by poking holes in these claims but by some honest doctors, as well as some fraudulent supplement companies and sellers. Why are some honest doctors on the line? Just true age reduction is pointless if the same effects are achieved, even somewhat slower, by other supplements being taken which have other positive effects as well! This is very controversial, in that honest doctors with guaranteed clinical tests are declared unnecessary! The essence of Dr. Sinclair's method is that most aging fix methods of the venerable "Hallmarks of Aging" are achieved by fixing the DNA, and [have been validated differently by me]!

Contributions?

Based on extensive biological knowledge over two decades, the essential technique I use to step around this crucial problem is to admit only supplements whose mechanism has been established. If the additional supplement has no additional benefits then the supplement is not used anymore unless a later study conclusively establishes a benefit beyond the period tried. Also, supplements with chemicals not needing a catalyst are not used since they are likely to interfere with some future medication. That is the primary reason for dropping quercetin.

Extension of what?

The principal benefit of Dr. Sinclair's theory of aging of Epigenetic repair is that most other ideas can be ignored because epigenetic repair will activate paths that will fix whatever damage is being fixed by most other claims, and worst case somewhat slower fix.

Dr. Sinclair's theory of aging is simple and short. Human DNA is overlain by epigenetic material that shows only some codons that correspond to codons turned on. The rest of the DNA is tightly coiled shut. Cells can fix their DNA breaks by shutting off reproduction during the fix. Aging (time) statistically causes failure in error correction. Broken cells lose identity and even cause CD38 protein damage to neighbors, eventually killing them. Old age is from this progressive positive feedback process. There are four fixes not fixed by epigenetic means. These make this departure from Dr. Sinclair, included as germane essential fixes after Sinclair, strictly chosen for mechanistic reasons, and are brain support, mtDNA (mitochondrial DNA) damage,  immune system loss,  and telomere shortening. These issues have been addressed already by literature, including by idiots who view their fix as complete-anti-aging.

How fix the brain?

Brain fix is what psychiatry is in general. It is challenging because of the censorship of blood-carried chemicals by the Blood-brain barrier. Also called Nootropic supplements use. I limit myself to fixes generally available as equivalent Ayurveda solutions for cost reasons and for additional non-modern medicine testing, especially brain chemicals. Only Ramdev solutions are sought for trust in the formulation and manufacture reasons only - never have or will trust Ayurveda.

Most chemicals are modern with known Ayurvedic equals. For example, Bacopa Monnieri is recommended, it same as Brahmi. The second essential is Ashvagandha. 

This is a broad subject with issues like Alzheimer's, Parkinson, etc, and will be dealt with in detail later. Another subject is forgetfulness believed to be caused in part by reducing short-term memory.

What happens with mtDNA loss?

Fixing mtDNA is for boosting strength, a common loss with age. All chemicals below are not needed. Choose a subset with physician help. Some NMN helps.

MtDNA fixes are by many methods. Mitochondrial DNA (mtDNA) is distinct from Human DNA and faces the universal challenges of genome maintenance: the accurate replication, transmission, and preservation of its integrity throughout the life of the organism. Although mtDNA was originally thought to be fixed in DNA repair activity, four decades of research on mitochondria have revealed multiple mtDNA repair pathways, including base excision repair, single-strand break repair, mismatch repair, and possibly homologous recombination. These mtDNA repair pathways are mediated by enzymes that are similar in activity to those operating in the nucleus, and in all cases identified so far in mammals, they are encoded by nuclear genes.

• Resveratrol or Pterostilbene - plant bacteria killers. It's already recommended.
•  Shilajeet! Ayurvedic is supposedly a great strength giver.
• L-Carnitine
• B Vitamins - great anyways. I use them as B-complex.
• Pyrroloquinoline Quinone PQQ - not eaten yet but highly recommended.
• Alpha Lipoic Acid ALA - Vitamin-like, very safe.
• Creatine - great strength booster, great with the gym.
• Magnesium - is as useful as calcium!
• CoEnzyme Q10 - great for the heart too.

The immune system?

It declines due to Thymus involution - it means progressive replacement by fat, complete by age 60. Some immune responses die by age 80 from the death of white cells still alive in the bloodstream to then. Life beyond to witnessed year 112 is Poisson distributed as expected.

The only good solution now is a vaccine whenever the expectant bacteria or virus is known. Best known are the flu vaccine and covid series vaccines. However, all system vaccines fail to novel evolutionary changes in pathogens and must be periodically retaken.

There are many advertised (no comment) solutions based on anti-oxidants, that may help (or not) sufferers but all have no effect like vaccines.

I have a new unicorn(!) method derived from CAR T cells like replacements for white cells by growing them in a hospital lab and later refusion, guaranteed free from rejection. In annual health checkups, sensible for all over 60. Another approach is through Dr. Fahy's methods.

How fix Telomere?

HBOT (Hyperbaric Oxygen Therapy), an aging application pioneered by Israel is the best. Old medicine wrongly believed that this alone was aging! Every cell division reduces cell telomere length within 2 years. 50-60 times later, all telomere is gone and the cell stop dividing. Telomerase enhances the length and is coded in DNA, made only in male eggs and discovered by all cancers, giving cancer cells bio-immortality. HBOT is useful for injuries and Film-artist looks, etc. Service centers already exist. A patented form increases telomere length akin to professional divers. I consider it another Unicorn startup in India with Israeli collaboration.

Dificult for me

 

Dearest Pasargad Arash

 

I am a very normal scientist with a penchant for multi-woman sex and you are in the stream of persons with many women of low character and potential. You are an exception and I have promised to self to always respect you, given the horrible things Iran does to women, far more evident even diluteing away BJP superconservative propaganda possibilities. You do not appear to be safe, happy, or enjoying life, despite wealth, looks and possible brains, all without fault.

 

If I look at all your pics, there is no smile as this pics over all times I have known you, this one must be older.

 

I am a very confident scientist and some day I will be able to appreciate you properly. A deeper secret for me is reducing age, works for me, look and feel 50, know true bio-age this may in the USA. Till then I have 3 foci, biology of aging, business practices, encryption. I sent you bombastic letter to which I am committed, even at potential of losing you.

 

Please avoid me, more than 1 per month, only because you understand me and my limitations, and not because I think of you not less than an angel who needs to be serenaded.

 

AAQ®STORY FOR OTHERS

 

The latest link

Let’s not go before 2000. At that time, I was determined to find out what JWST-telescope in 2011 at L2 reveals about the Universe, for I am then an agnostic Hindu who only accepts atheistic science stories. Then a British computer scientist who then did MD and was chairman of the medical department at Cambridge for old visited MIT and spoke about scientific 1000-year life and was given a tough time by kid students. Did not faze him and replied logically. This piqued my interest in biology. Then in 2005 funded magic medical research 2005 that performed the first parabiosis surgery that showed age reduction with the surgical joining of old to young. Simple blood transfusion of young blood was useless and Spanish work showed that simple blood thinning was sufficient by 2015, the door was shut further in 2120 tests by the same couple. 

This was subsequent to another great thread that found great synergy between AI-interpolated Cp islands in DNA and bio-age that also correlated with time to death. 

The third great thread was the OSKM conversion of any DNA by Yamanaka into pluripotent DNA by 2014, the established science date. Since then, just OSK is found sufficient without M, which does not start cancers. Some more things can speed up OSK. Intermittent OSK slowly fixes DNA only somewhat without causing DNA memory breach beyond whatever DNA is now. There are no evil side effects long-term. Dr. Sinclair at Harvard medical school has used OSK to move the age of mice back and forth at will in a paper published in 2023. I happen to be 99% confident that they will work in humans same way,

 By 2025, human clinical tests will be done to allow rational-danger persons like me to start using them. Good bio-immortality will keep me alive until then. Even a 2027 date looks reasonable.

Some degree of age fix can be done by NMN and forced elimination of apoptosis-avoid cells. This does not address other one-shot methods based on top-down organ and stem cell aging and immunology losses from thymus aging, etc. Or the critical telomere shortening, erroneously considered actual aging fic by medical schools and manifest by failure to reproduce beyond 50-60 times. 

The fourth great thread is the HBOT method to fix and refix telomere issues. This was pioneered in 2022.

The point is that OSK methods are likely to be for repeated use. Once basic losses are solved by NMN and Spermdine/Fisetin solutions, OSK solutions can wait. OSK methods will not fix all interventions needed and usual medication and strength methods will continue.

Almost all chemicals needed are available today in India. Still not liposome. I am warm on aging startup, Starting after 3 months.  Expenses are 3-4 lakh rupees or $4-5 THOUSAND! per year for a guaranteed 1 year or more reduction in age. Expect it from proper life and exercise alone! Why trust me? Used my treatment on myself, look in my fifties when seventy, USA bio-age (whatever). How much 1 year worth to you!! Will register AAQ, and patent its use inside a word, soon. Note that the use of the LIPOSOME form for all medicines is new, if can do it by a straight-forward machine means unicorn status is guaranteed. Not essential but useful.

It is wrong to believe that once chemicals are known, all else follows. Morning/lunch/dinner, before or after meals and gap, how many grams, who to buy from, etc. cannot be answered! Even one small error in medication amount or small failure deviating from the doctor's explained schedule can be life-threatening or FATAL. NMN and apoptosis-force drugs are all you need, but Caakg and glycine are being tested. They are a dozen drugs I have tried, every 4 months, whether made a significant difference or not. Readers, basing trust on any method using any advertisement except my error-prone method, are emfubar idiots.