Monday, March 6, 2023

Why engineering immortality


Abstract             Not so, but other competing ideas                   Latest version link

[[...] surround links] are basic to running text and are mine. Other links are references for credibility. If immortality is possible then why don't we see it? This is the babble of mentally deficient who fail to understand engineering, always working within current science to construct disruptive novel realities like los alamos, fusion, etc. It is about the existence of a limited doable estimable program.

[Negligible Senescence]

I consider it my masterpiece of 22 years of work that describes a low chance but achievable immortality, desired by humans, with a purpose, without the religious/spiritual stupidity with a nonsensical soul or any sci-fi. Never has any author in human history, found a believable engineering solution to immortality and purpose without invoking untestable facts or infinite science. As a critic, do not put your toes in your mouth by failing to click [...] links that will tell you how the header text linked is done by me.

[This essay is about the true engineering of immortality] and what to do in the time triumphally extracted from nature. Regardless of deprecated other obscene associated meanings,  triumphalism defines me in victory over one supposed axiom of nature even if by those that revile the U.S.A. or engineers as a satanic worry, saying everything has an eventual end. Life need not be a short episode.

 Three issues are how seek immortality, why get it, and dismissal of other pretenders or claimants. Even extension to 1000 years will be welcomed by my children, who can extend it some, and so on.

The Dismissal of other claimants?

Engineering, despite close association with science, trumps it for practicality. This is eng-fi based on engineering based on existing science that never postulates the end. The essential difference to sci-fi is the ability to make firm time estimates based on challenges to top engineers, a central author coined test to deal [with inadequate Popperian falsifiability].  Estimate failure improves falsifiability.

All other claimants based on any religions, spiritualism, pseudoscience, seniority, politics, etc. fail before certain immortality of something akin to the soul or other not realized sciences are useless as they do not allow meaningful time estimates by the majority of existing recognized engineers. Cryopreservation of the body is a sci-fi method rejected for the failure of any time estimates. Same reasoning destroys Jules Vern and its style passage to moon.

How to get it?

Basic to getting true immortality is first defeat aging to bio-immortality first.

1. [Defeat DNA aging]

2. [Defeat other agings]



At this point, you are bio-immortal but still vulnerable to other physical methods. Bio-immortality is not necessarily unusual. It follows from negligible senescence. It is seen in lobsters, crocodiles, whales, etc. None including humans are safe from death by predation and cancers. These animals ultimately die from predation or cancers, etc. Only a technology-developing species like us humans can achieve technology from fast evolution to develop cures for cancers, all other dangers and negligible senescence. Rejuvenation is better than deaging

Full immortality is possible only on brain download based on MIT-developed technology. The brain is first expanded to a huge size. Technology exists for transit to a cyborg's brain. The download can be preserved against all modes of destruction as well as timeless travel between stars as photons experience no time and can travel between stars redundantly.

Many techniques are much better done by printed parts stitched by AI that has associated dangers operating by itself, but I consider humans to evolve into cyborgs.

3. [Why Full immortality]

Do what with it?

The download can be preceded by vastly accelerated travel within our solar system and nearby stars using dynamic soaring. It gives meaning to life (travel in the universe) and eventually moves to another multiverse object in the final phase in some sci-fi way!

4.[ travel the universe]

5. [transit stars and galaxies]

Author note

This is an eng-fi version, it amazes me that despite the sci-fi look, no new science is needed, bio-immortality is possible, and I am a serious believer and self-apply it.  There is a known limitation of NMN, namely 15-20 years of life. However, the one more applicable and likely good for repeated use for 10,000 years is already being researched and likely to use in 5 years, being based on OSK Yamanaka factors, likely widely available at a reasonable price in 7-10 years. That is within my natural life span, also before my white cells die, my current supplements give me life and more, the strength to exercise. I look 50 and look 50-60 when Yamanaka factors are done. There will never be a need for any other age-assist supplement mix! I have many unicorn ideas

1. Software for quantum computer secure encryption, recently beyond classic computers

2. One-time age retraction to 10-20 years for age 60-70 years persons

3. White cell lab growth and re-fusion for age 60-80 years

4. HBOT experiments on mice for telomere fix and practice

5. Liposome forms of all powder form prescription medicine made by UP/India lipo-makers

and will do them full time now and spend real money, possible only in India, with USA SS help. Simple no hypocrisy means I may be wrong, unlikely as not costing money and not funded and claiming to have no reason. I do it for acknowledged support for the USA SS in my TBI, hoping that the need will vanish some day in my life. Law provides for that.


Saturday, March 4, 2023

2023 anti-aging



Latest self-link [DNA aging +]

Anti-aging so far: must understand Dr. Sinclair's style aging fix, this is more. Death can come in many ways covered in my hyperfunction theory. The earliest death is enough. That you are protected from most subsequent deaths is irrelevant.

The problem?

Anti-aging is not a genuine modern medicine subject but a true engineering subject. I have designed and used on myself a cocktail of supplements. These are mostly non-medicine, FDA has no business regulating me. My self-clinical experience has decompressed some claims by poking holes in these claims but by some honest doctors, as well as some fraudulent supplement companies and sellers. Why are some honest doctors on the line? Just true age reduction is pointless if the same effects are achieved, even somewhat slower, by other supplements being taken which have other positive effects as well! This is very controversial, in that honest doctors with guaranteed clinical tests are declared unnecessary! The essence of Dr. Sinclair's method is that most aging fix methods of the venerable "Hallmarks of Aging" are achieved by fixing the DNA, and [have been validated differently by me]!

Contributions?

Based on extensive biological knowledge over two decades, the essential technique I use to step around this crucial problem is to admit only supplements whose mechanism has been established. If the additional supplement has no additional benefits then the supplement is not used anymore unless a later study conclusively establishes a benefit beyond the period tried. Also, supplements with chemicals not needing a catalyst are not used since they are likely to interfere with some future medication. That is the primary reason for dropping quercetin.

Extension of what?

The principal benefit of Dr. Sinclair's theory of aging of Epigenetic repair is that most other ideas can be ignored because epigenetic repair will activate paths that will fix whatever damage is being fixed by most other claims, and worst case somewhat slower fix.

Dr. Sinclair's theory of aging is simple and short. Human DNA is overlain by epigenetic material that shows only some codons that correspond to codons turned on. The rest of the DNA is tightly coiled shut. Cells can fix their DNA breaks by shutting off reproduction during the fix. Aging (time) statistically causes failure in error correction. Broken cells lose identity and even cause CD38 protein damage to neighbors, eventually killing them. Old age is from this progressive positive feedback process. There are four fixes not fixed by epigenetic means. These make this departure from Dr. Sinclair, included as germane essential fixes after Sinclair, strictly chosen for mechanistic reasons, and are brain support, mtDNA (mitochondrial DNA) damage,  immune system loss,  and telomere shortening. These issues have been addressed already by literature, including by idiots who view their fix as complete-anti-aging.

How fix the brain?

Brain fix is what psychiatry is in general. It is challenging because of the censorship of blood-carried chemicals by the Blood-brain barrier. Also called Nootropic supplements use. I limit myself to fixes generally available as equivalent Ayurveda solutions for cost reasons and for additional non-modern medicine testing, especially brain chemicals. Only Ramdev solutions are sought for trust in the formulation and manufacture reasons only - never have or will trust Ayurveda.

Most chemicals are modern with known Ayurvedic equals. For example, Bacopa Monnieri is recommended, it same as Brahmi. The second essential is Ashvagandha

This is a broad subject with issues like Alzheimer's, Parkinson, etc, and will be dealt with in detail later. Another subject is forgetfulness believed to be caused in part by reducing short-term memory.

What happens with mtDNA loss?

Fixing mtDNA is for boosting strength, a common loss with age. All chemicals below are not needed. Choose a subset with physician help. Some NMN helps.

    MtDNA fixes are by many methods. Mitochondrial DNA (mtDNA) is distinct from Human DNA and faces the universal challenges of genome maintenance: the accurate replication, transmission, and preservation of its integrity throughout the life of the organism. Although mtDNA was originally thought to be fixed in DNA repair activity, four decades of research on mitochondria have revealed multiple mtDNA repair pathways, including base excision repair, single-strand break repair, mismatch repair, and possibly homologous recombination. These mtDNA repair pathways are mediated by enzymes that are similar in activity to those operating in the nucleus, and in all cases identified so far in mammals, they are encoded by nuclear genes.

    The immune system?

    It declines due to Thymus involution - it means progressive replacement by fat, complete by age 60. Some immune responses die by age 80 from the death of white cells still alive in the bloodstream to then. Life beyond to witnessed year 112 is Poisson distributed as expected.

    The only good solution now is a vaccine whenever the expectant bacteria or virus is known. Best known are the flu vaccine and covid series vaccines. However, all system vaccines fail to novel evolutionary changes in pathogens and must be periodically retaken.

    There are many advertised (no comment) solutions based on anti-oxidants, that may help (or not) sufferers but all have no effect like vaccines.

    I have a new unicorn(!) method derived from CAR T cells like replacements for white cells by growing them in a hospital lab and later refusion, guaranteed free from rejection. In annual health checkups, sensible for all over 60. Another approach is through Dr. Fahy's methods.

    How fix Telomere?

    HBOT (Hyperbaric Oxygen Therapy), an aging application pioneered by Israel is the best. Old medicine wrongly believed that this alone was aging! Every cell division reduces cell telomere length within 2 years. 50-60 times later, all telomere is gone and the cell stop dividing. Telomerase enhances the length and is coded in DNA, made only in male eggs and discovered by all cancers, giving cancer cells bio-immortality. HBOT is useful for injuries and Film-artist looks, etc. Service centers already exist. A patented form increases telomere length akin to professional divers. I consider it another Unicorn startup in India with Israeli collaboration.

    Dificult for me

     


    Dearest Pasargad Arash

     

    I am a very normal scientist with a penchant for multi-woman sex and you are in the stream of persons with many women of low character and potential. You are an exception and I have promised to self to always respect you, given the horrible things Iran does to women, far more evident even diluteing away BJP superconservative propaganda possibilities. You do not appear to be safe, happy, or enjoying life, despite wealth, looks and possible brains, all without fault.

     

    If I look at all your pics, there is no smile as this pics over all times I have known you, this one must be older.

     

    I am a very confident scientist and some day I will be able to appreciate you properly. A deeper secret for me is reducing age, works for me, look and feel 50, know true bio-age this may in the USA. Till then I have 3 foci, biology of aging, business practices, encryption. I sent you bombastic letter to which I am committed, even at potential of losing you.

     

    Please avoid me, more than 1 per month, only because you understand me and my limitations, and not because I think of you not less than an angel who needs to be serenaded.

     

    Wednesday, March 1, 2023

    AAQ®STORY FOR OTHERS

     



    The latest link

    Let’s not go before 2000. At that time, I was determined to find out what JWST-telescope in 2011 at L2 reveals about the Universe, for I am then an agnostic Hindu who only accepts atheistic science stories. Then a British computer scientist who then did MD and was chairman of the medical department at Cambridge for old visited MIT and spoke about scientific 1000-year life and was given a tough time by kid students. Did not faze him and replied logically. This piqued my interest in biology. Then in 2005 funded magic medical research 2005 that performed the first parabiosis surgery that showed age reduction with the surgical joining of old to young. Simple blood transfusion of young blood was useless and Spanish work showed that simple blood thinning was sufficient by 2015, the door was shut further in 2120 tests by the same couple. 

    This was subsequent to another great thread that found great synergy between AI-interpolated Cp islands in DNA and bio-age that also correlated with time to death. 

    The third great thread was the OSKM conversion of any DNA by Yamanaka into pluripotent DNA by 2014, the established science date. Since then, just OSK is found sufficient without M, which does not start cancers. Some more things can speed up OSK. Intermittent OSK slowly fixes DNA only somewhat without causing DNA memory breach beyond whatever DNA is now. There are no evil side effects long-term. Dr. Sinclair at Harvard medical school has used OSK to move the age of mice back and forth at will in a paper published in 2023. I happen to be 99% confident that they will work in humans same way,

     By 2025, human clinical tests will be done to allow rational-danger persons like me to start using them. Good bio-immortality will keep me alive until then. Even a 2027 date looks reasonable.

    Some degree of age fix can be done by NMN and forced elimination of apoptosis-avoid cells. This does not address other one-shot methods based on top-down organ and stem cell aging and immunology losses from thymus aging, etc. Or the critical telomere shortening, erroneously considered actual aging fic by medical schools and manifest by failure to reproduce beyond 50-60 times. 

    The fourth great thread is the HBOT method to fix and refix telomere issues. This was pioneered in 2022.

    The point is that OSK methods are likely to be for repeated use. Once basic losses are solved by NMN and Spermdine/Fisetin solutions, OSK solutions can wait. OSK methods will not fix all interventions needed and usual medication and strength methods will continue.

    Almost all chemicals needed are available today in India. Still not liposome. I am warm on aging startup, Starting after 3 months.  Expenses are 3-4 lakh rupees or $4-5 THOUSAND! per year for a guaranteed 1 year or more reduction in age. Expect it from proper life and exercise alone! Why trust me? Used my treatment on myself, look in my fifties when seventy, USA bio-age (whatever). How much 1 year worth to you!! Will register AAQ, and patent its use inside a word, soon. Note that the use of the LIPOSOME form for all medicines is new, if can do it by a straight-forward machine means unicorn status is guaranteed. Not essential but useful.

    It is wrong to believe that once chemicals are known, all else follows. Morning/lunch/dinner, before or after meals and gap, how many grams, who to buy from, etc. cannot be answered! Even one small error in medication amount or small failure deviating from the doctor's explained schedule can be life-threatening or FATAL. NMN and apoptosis-force drugs are all you need, but Caakg and glycine are being tested. They are a dozen drugs I have tried, every 4 months, whether made a significant difference or not. Readers, basing trust on any method using any advertisement except my error-prone method, are emfubar idiots.

    Tuesday, February 28, 2023

    Más - El viaje interestelar de mi vida

     


     

    ¿De qué se trata esto?


    Esto no es ciencia ficción, sino mi ficción de ingeniería definida o eng-fi, diferente ya que no se asume ninguna ciencia nueva y, por lo tanto, es posible una estimación de tiempo significativa. Se trata de ir a la estrella más cercana y vivir lo suficiente para verla en mi vida.

    Los humanos viajan interestelar, sin descubrir cosas nuevas de ciencia ficción como agujeros de gusano o rupturas significativas en el impulso warp. Que pueda ser así en mi vida es vivir hasta 2090 o más, dado que no se supone ningún progreso adicional en los próximos 80 años, el crecimiento mínimo esperado de salud por la tecnología actual, como esta carta https://aaqg-arunarya.blogspot.com /2023/01/spanish-living-to-2090.html muestra, basado en este ensayo https://aaqg-arunarya.blogspot.com/2023/01/latest-link-on-recommended-anti-aging.html.

     

    ¿Y cuándo sucede dado el retraso del envejecimiento?


    Escribo solo ficción de ingeniería, diferente de la ciencia ficción, basada solo en la ciencia existente y, por lo tanto, puedo establecer estimaciones de tiempo basadas en los desafíos para ingenieros de alta calidad. Estimo entre el 100 aniversario del lanzamiento del sputnik en 2061 y la celebración del centenario del alunizaje en 2069. Misión de 14 a 20 años a la estrella más cercana, incluido el retorno de luz de datos de 4 años. Voy a estar allí.

     

    ¿Por qué es mala la propulsión química, a pesar de la reutilización muskiana?


    Ecuación del cohete, https://qph.fs.quoracdn.net/main-qimg-56852104cc5542d450eb04e290160a7f derivada de la conservación de la energía y el momento. ¡Muestra que el aumento en la velocidad es proporcional al logaritmo de la masa del cohete expulsado, a pesar de cualquier tecnología excepto un cohete con motor de antimateria! ¡Cualquier cohete, incluida la fusión, no podrá siquiera obtener una fracción sustancial de la velocidad de la luz! Entonces, solía pensar que un problema se resolverá después de los próximos millones de años, con mucho tiempo para recolectar las cantidades requeridas de antimateria. ¡Pero ya hay tres formas de enviar misiones de cámara! Y 1 para enviar humanos a finales de siglo.


    2 son para esquivar la ecuación del cohete al no expulsar masa del cohete. Una es encontrar antimateria en cantidades de toneladas.


    1. Método de tiro de ruptura


    Toda la nave espacial, la cámara y la electrónica de retorno de señal y la antena están miniaturizados a un tamaño de 1-2 g. A continuación, una nave espacial se dirige al área objetivo de un enorme láser en la Tierra. Varios miles de copias de la nave espacial serán aceleradas en el mismo viaje. Cada nave espacial tiene una vela grande (material o magnética) que es el objetivo de un láser terrestre, como en chile. ¡Las naves espaciales de chips sin humanos pueden tolerar fácilmente aceleraciones de 10,000 a 100,000 * g y pueden enviarse al siglo alfa-0 en un día! Al menos 1 de cada mil sobrevivirá; se espera una concentración molecular de 1 por metro cuadrado. Y varias cosas pueden mejorar las posibilidades.


    2. Los cuerpos de antimateria se encuentran en el sistema solar.


    Eso es probable dado que una cámara de la NASA ha detectado algunas moléculas de antimateria en sus escaneos. Es probable que Sun haya estado produciendo algunos nano g de antimateria por año durante 5 mil millones de años. Si se recolectaron en algún lugar, probablemente porque el telescopio no ve eventos de extinción durante décadas, ¡tal vez se encuentren!


    3. Este es un nuevo método asombroso basado en el vuelo dinámico. Los planeadores que vuelan entre dos corrientes a diferentes velocidades pueden alternar entre ellas e ir mucho más rápido que cualquiera de las corrientes a 850 mph, ¡sin importar si no tienen combustible! Las aves pueden volar en bucles y obtener impulsos sustanciales. ¡El albatros puede recorrer 5000 km por semana, ha sido documentado, hecho repetido! ¡Cerca del nivel del mar, el aire está en calma y el viento sopla con frecuencia a 300 pies! El sol sopla viento solar más lento en la parte superior y más rápido en el ecuador.


    Ahora para la ciencia. La energía cinética es 0,5 *m * cuadrado(v). ¡Usando la ecuación del cohete, se puede demostrar que un cohete químico necesita la masa del resto del universo para ir a la estrella más cercana! Pero, ¿y si la mayor parte de la energía proviene de un evento astronómico de una corriente de dos velocidades, que es independiente de la masa y no es transportada por un cohete? De hecho, ¡parte del cohete tiene algo de masa para ser expulsado a velocidades muy altas! ¡Ahora la energía aumenta aún más, a velocidades muy altas solo para un impulso más rápido! Se puede llegar al 1% de la velocidad de la luz relativamente rápido gracias al viento solar. El aumento al 50% de la velocidad de la luz ocurre en la heliopausa y uno tiene una gran cantidad de masa de pérdida rápida para luego hacer el resto de la brecha en 1-2 años. Mucha masa para acelerar hasta 50% veces la velocidad de la luz.


    A esas velocidades, incluso la colisión con suciedad a nivel de molécula será fatal. Sin embargo, las barreras magnéticas pueden defendernos de este tipo de problemas. De hecho, se necesita un gran nivel de ingeniería y dinero. ¡Pero la ciencia está ahí! No se requiere para un reclamo de ruptura de viaje solar e interestelar.


    ¡Otra idea es rociar un poco de suciedad anterior en la dirección de avance, destruir cualquier basura pequeña que se acerque y recuperar el rocío mediante una pantalla desplegada en el punto más avanzado para reutilizarlo volviendo a rociar más adelante!


     

    ¿Qué cosas nuevas pueden venir con la bio-inmortalidad y este avance?

    La estrella más cercana es Proxima Century, que tiene un planeta un poco más grande que el planeta Tierra en la zona Gold-i-Lock, y está bajo una intensa observación del telescopio web JWST, que dice que el mejor objetivo para él está perfectamente bloqueado en la estrella. como la luna a la tierra, sin giro relativo. Así que el mismo lado mira hacia el sol.


    La parte que da al sol es muy caliente y el otro lado está en perpetua oscuridad y muy frío. Incluso esos lugares pueden tener nueva vida cerca del divisor y JWST puede buscar luces artificiales, muy mal, pero parece haberlas encontrado (James Webb Telescope Detected Artificial Lights On Proxima B https://www.blog.sindibad.tn/ james-webb-telescope-detected-artificial-lights-on-proxima-b , también ALMA detecta luz artificial en Proxima B https://seriesstories.com/james-webb-telescope-detects-artificial-light-on-proxima- b/)! En última instancia, esperamos los telescopios sucesores en 2035 y el viaje de una cámara robótica al planeta.


    ¿Por qué le temes a la competencia de Estados Unidos?


    Una competencia amistosa y bienvenida a la NASA. Valida la entrada gratuita de varias décadas y algunos controles manuales. Incluso NIAC apoya esta dirección. ¿Por qué llamo a nuestros Astrocientíficos?


    1. Es factible.

    2. Mucho más barato que los EE. UU.

    3. Necesita y ofrece la miniaturización de todos los componentes: eléctricos, electrónicos, fotónicos, mecánicos, de propulsión, etc. Cada uno de estos avances tecnológicos tiene inmensos beneficios colaterales.

    4. Tendrá aplicaciones vírgenes en nuestro sistema solar, ganemos o no la competencia interestelar. La más deseada es la minería de asteroides.


    ¿Y por qué la NASA debería llevarse toda la gloria?


    Los astrocientíficos indios pueden hacer un proyecto a bajo costo, una vez que el gobierno acepte la producción de miniaturización de chips, que ya es un proyecto de gran importancia por separado. No importa, la nave espacial robótica interestelar rápida nos brinda una oportunidad encantadora y útil de los planetas solares, miles de millones de objetos del cinturón de Kuiper e incluso billones de habitantes de la nube de Oort.


    ¿Qué significa este proyecto para ti?


    Neptuno en 1,5 años, ¿alguien? ¡Servicio de autobús entre la tierra y marte! ¡Cualquiera que prediga que me aburriré durante los próximos 1000 años está loco! Los árboles longevos igualan vida para mí. La vida cargada significa 10000 años y la derrota de todos los demás modos de muerte y viajes a la velocidad de la luz, viajes universales no aburridos. El viaje rápido óptico sin aburrir es para un millón de años. Hay un gran universo ahí fuera. El viaje óptico podría ser de mil millones o billones de años. Es tiempo suficiente para pensar en los próximos cuatrillones de años. Las estrellas comenzarían a morir sin reemplazo entonces. Viajar a otros objetos de múltiples versos te mantiene ocupado cuatrillones de años viviendo en agujeros negros mientras tanto.




    Friday, February 24, 2023

    Phillipines


     Language and Vocabulary

    It is evident that the Filipino language and vocabulary was strongly influenced by the original Sanskrit. Local words like Guro (teacher) came from the Hindu word Guru. Karma, a Hindu concept, is culturally understood by Filipinos. The following are some of the Sanskrit words used in the Filipino. • bahagi (part, portion) in Tagalog, is bhag in Hindi, • diwata (god or goddess) is devata • dukha (poor, destitute) is duhkha • guro (teacher) is guru • katha (story, fiction) is katha • mukha (face) is mukha • yaya (nurse) is aya
    Hinduism Today
    Actual followers of Hinduism are mostly confined to communities of indigenous and native people as well as new converts. Nowadays, there are new noticeable Hindu practices like Yoga and meditation. The presence of various Hare Krishna groups like Sai Baba, Paramansa Yoganda (SRF) and Mekha Baba are also evident.