Wednesday, September 1, 2021

Study of the AVIV paper


 

After writing: Judged erroneous, not amrit, coz extension of telomeres does not reduce age! BUT Katcher E5, under tests, amazed the greats by actually reducing age, hence real amrit when a product.


 Latest link        before    next link

The study is a mark-up of the document. Original text is like this.

My comments are like this.



Received: September 3, 2020       Accepted: October 22, 2020       Published: November 18, 2020

https://doi.org/10.18632/aging.202188
How to Cite

Copyright: © 2020 Yafit et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 


    This is one year old, escaped me, not recognised as not discussed as the greatest disruptive research it is, but caught within a year by me who acts to exploit the biggest opportunity in most lives. I believe in it despite knowing that biggest fraud in last 4000 years is age boost!

Abstract

Introduction: Aging is characterized by the progressive loss of physiological capacity. At the cellular level, two key hallmarks of the aging process include telomere length (TL) shortening and cellular senescence. 

    Aging is best defined as a biological process with aging hallmarks. The Hallmarks of Aging. Of 9, they focus on 2.

Repeated intermittent hyperoxic exposures, using certain hyperbaric oxygen therapy (HBOT) protocols, can induce regenerative effects which normally occur during hypoxia. The aim of the current study was to evaluate whether HBOT affects TL and senescent cell concentrations in a normal, non-pathological, aging adult population.


    Their magic is several hyperoxic and hypoxic cycles per session Rejuvenation occurs in hypoxia part of the cycle. This is like intermittent muscle strengthening. They do not disclose how many cycles per session or details of oxygen waveform. Reverse engineering may have to be done. Mice models will be needed for these engineering details. I assume that 12 week, 5 times 2 hour sessions per week can be copied at this point. Triangular face mask type HBOT allows chair sitting and can be modified to sit on exercise bike!


Methods: Thirty-five healthy independently living adults, aged 64 and older, were enrolled to receive 60 daily HBOT exposures. Whole blood samples were collected at baseline, at the 30thand 60th session, and 1-2 weeks following the last HBOT session. Peripheral blood mononuclear cells (PBMCs) telomeres length and senescence were assessed.


    We can enrol Indians from low classes for three month. Wages can be paid, boon for retirees at 65. The aging benefits are there! In fact, many people will pay to be in the study. One machine can be used by 12 people.


Results: Telomeres length of T helper, T cytotoxic, natural killer and B cells increased significantly by over 20% following HBOT. The most significant change was noticed in B cells which increased at the 30th session, 60th session and post HBOT by 25.68%±40.42 (p=0.007), 29.39%±23.39 (p=0.0001) and 37.63%±52.73 (p=0.007), respectively.


    It is medicine saying that if the immune system can be saved from time, a person can live for 1000 years! All the benefits above are in the immune system in human blood.


There was a significant decrease in the number of senescent T helpers by -37.30%±33.04 post-HBOT (P<0.0001). T-cytotoxic senescent cell percentages decreased significantly by -10.96%±12.59 (p=0.0004) post-HBOT.


    Fixing the immune system is by lengthening the telomere and by garbage-collecting the senescent cells. Both are being done! Low cost small delta  variations can be tried in India, and only here!

In conclusion, the study indicates that HBOT may induce significant senolytic effects including significantly increasing telomere length and clearance of senescent cells in the aging populations

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