Mind you, while goal is immortality, I refuse to take risks to equally
satisfactory amortality (diseased only at ends). Diabetes
Drug Metformin Could Slow Down Aging Process, Let Us Live 120+ Years!
BTW 99.99% religious and 75% doctors indifferent to bio-chemist living in
wolkencuckosheim of ancient medical college and books are STUPID, if you have
better numbers for either, stop right here!
In general, I ignore the legal system as easily bamboozled
morons when it comes to medicine and science, particularly which doesn’t
self-recognize lawyers bullshit and take corrective steps! Quintessential example is allowing
fats to be blamed in diabetes and 40 year legal delay in stevia. There is nothing
stupider than a judge trying to
synthesize conflicting expert testimonies without an imposed external
philosophy of science, proficiency required! At least, the imposition will
improve on errors!
Calcium and iron deficiencies are not uncommon in
diets in developing countries where less meat is eaten and there is high
consumption of phytic acid from beans and unleavened whole grain bread. Calcium-deficiency causes osteoporosis while
Fe-deficiency is anemia,
both widely prevalent in india hence guilty-unless-innocent! Both reduce age also
bad symptoms on aging ie anti-amortality in my neologism.
Mitochondria have 3 energy cycles, replenished by
monosacchrides from food – citric acid, atp-adp, nadh-nad+; increasing importance, energy-reduced order.
Anti-oxidant
class: for NAD+ and NADH: The
energy storage in body uses Mitochrondia as chargeable cells. Electrons move
from NADH to discharge as NAD+. Food recharges again. There is no direct path
to NADH. NAD+ can be generated two ways – de novo - fresh new by amino acid
synthesis and by salvage cycle. Nad+ increase is desired. Precursor are fastings,
exercise, calorie-restriction and chemicals.
Each has a sweet spot, utility falls after. Too much fasting,
calorie-restriction, exercise or chemical-precursor are harmful. Easiest and 99%
thuggery of partial morons is in chemical-precursor where bio-availability
matters and a thug-criminal can truthfully claim precursor-ness. You can do do
better two ways – increase nad+ or decrease the oxidation junk.
Nad+ can be
increased in many ways – (its salt).
This list is NOT ordered by percentage or importance or free of BAD effects
(like FAT). Its value-free scientific list. Needed for understanding exceptions.
– indicates self-adopted. ? is may.
·
o - 7) Fructose
Possibly dangerous Supplement chemicals
Supplements
to Increase NAD+
- Nicotinamide
Riboside
- Oxaloacetate
- Malic acid (R)
- Resveratrol (R)
- Apigenin (R)
- Leucine (R)
- Niacinamide – low doses (R).
- Lithium inhibits
mir-34a, which inhibits NAMPT, the enzyme that makes NAD+ (R)
So lithium should technically increase NAMPT
and NAD+ by taking the breaks away from its production.
- Succinic acid – to a lower
degree than malate (R)
Next what to avoid, if possible, that increase ageing rates.
o 2) Disrupted Circadian Rhythm (sleep-wake)
Anti-oxidants reduce the wastage from
oxidation in the cycle. An antioxidant is a molecule that
inhibits the oxidation of other molecules. Oxidation is a chemical reaction that can produce free radicals, leading to chain reactions that may damage cells. Antioxidants such as thiols or ascorbic acid (vitamin
C) terminate these chain reactions. The term "antioxidant" is mainly
used for two different groups of substances: industrial chemicals which are
added to products to prevent oxidation, and natural chemicals found in foods
and body tissue which are said to have beneficial health effects.
The oxidation junk produced accumulates – that is what aging
is. Key preventions are anti-oxidants like resveratrol, glutathione
Drug class: For
ATP-ADP cycle, best is metformin.
I am scared of new ones, accepting ONLY with century use (
i.e. GRAS and beyond), hence stevia is ok, Atkin’s diet is ok despite expert
noises. The legal system has no techniques in importance management beyond the
dumb dice-roll of higher court allowance to listen! Fortunate to me, enough
hard work has been done to distil to three chemicals and organise methods
around them.
A
miracle drug is metformin used for 1st line diabetes-2 drug, safe
enough to be used in non-diabetic. Available as plant product from Goat's rue, French lilac,
Italian fitch, and professor weed are all names for the same plant:
Galega officinalis.
Beside
anti-aging and anti-diabetes, metformin is also useful for anti-cancer. Safe enough
to be used by non-diabetic. Historically, plant extracts have been used in Europe to treat
plague, worms, snake bites, miasma, dysuria and St Vitus dance..
Rejected hence
are precursor-chemicals and HGH (human growth hormone) after dispassionate
extensive study.
rejected
1
hum,anm growth harmone
wish
stem
cells: Based on functioning of trees with 4000 year life span, it appears that not much selectivety is required and pluripotent stem cells take over automatically nearby (touching?) normal cells on failure. Hence I would like to see some experiments irrigating dividing cells by iPS cells and determining failures after the new division. In humans, the cells could be placed by injecting diseased ssites by injecting.
NAD :
Nicotinamide adenine dinucleotide - Wikipedia,
https://www.wikiwand.com/en/Nicotinamide_adenine_dinucleotide
severe problems
weight
exposure
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