Thursday, May 31, 2018

Aging – Sinclair view over all others


Sinclair is an MD, faculty in Harvard medicine, MD-PhD with MIT. His views are minority but being adopted explosively fast.
What is the basis of fame?
Yeast, made of very simple cells in a colony, suffers from aging! What is more, it can be studied fast. Using yeast, he found aq number of genes related to Sir genes. 7 are found in human, called Sirtuins, of which Sirt1 is the most prominent.
One entire line of medicine is focussed on anti-oxidants. Another attempts to understand two techniques, applicable to many species that have demonstrated benefits but are difficult to adopt – calorie restriction (hunger) and exercise (tiring). Both have molecular basis that may be amenable to much easier adoption, or even act as to increase the effectiveness of these two techniques.
Cutting through the chemistry thicket is the block diagram above. Of the three pathways, two are benefitted by metformin and nmn (nicotinamide mono nuclide). Upto last year, nmn was $2000 year per month of recommended dose. Two great things have happened since
1 Direct synthesis of nmn has been discovered
2 Sublingual administration of nmn is shown to be possible and effective so that stomach penetration losses can be avoided (sharply reducing required dosage) and 4 or more divided doses  per day is feasible.per day are feasible
THIS MEANS, STARTING JUNE 15, IN usa, A 500 MG/DAY DOSE PER DAY, DIVIDED INTO 4 OR MORE SUBLINGUAL SUBDOSES IS POSSIBLE FOR ANNUAL $500.
What does it mean to oxidant-guy like you?
Above indicates a tectonic shift in my thinking away from anti-oxidants to helper molecules. Why?
1 Beliveable partial empirical proof. The doctor takes his drugs as does his father. Doc claims feels like 30 when 60 (looks so too in video linked!) and wears no makeup! Father in 70’s claims feels 50’s.
2. Metformin (10,000,000) records and nmn (3 year human, countless mice) is safe.
3. Program is easy, super-easy for me who needs metformin for diabetes! 500 mg of nmn as four or 5 sublingual sub-doses, 4 times a week, supplement day 300 kcal exercise. Two dinners off per week. Age ninety, here I come, expecting to make 2050 decade, current tech, despite diabetes and heart triple bypass! Plenty of time to acquire boost and live past current expectation.
4 Plausible narrative, experiment worthy, low risk. Results can be visible within 3 months! So blow $200, limited risk.
Three ingredients of belief in my epistemology (absent credible attacks) are sho benefit, show safety and affordable! All met. Further requirement is short interval (3 month). If no visible benefits in 3 months then bye bye.

How come you trust him so much?
1 Experiments on himself and loved


2 Critical of own Reservetrol (sold for 750 million dollars. Empirical disaster from sales process losses and stomach barrier!
3 Avoids the glamourous but FDA-avoid route to FDA welcome to test
4 Hard won NASA commission to supervise health of Long-term astronauts to Mars

Friday, May 25, 2018

Why deaths – road, medical, crime etc – aaquantum scholarly research



There are commonalities deducible from hard statistics, not chosen. First rod then medicine Finally crime. Suggest from statistics is that causes can be divided into controllable and uncontrollable factors; different degrees of loss of liberty in remedial steps is involved; politicians, lawyers and law enforcement and philosophers who do not consider liberty-loss in suggestions upfront and fail to identify this consequence of trade-off up front are motherfucker criminals.

They must be severally punished in my ideology which only respects limited “no law, no crime” i.e. forbid of retroactive crime, not prohibited but subject to “prohibited, unless necessary” like “guilty, unless innocent” philosophy. This allows criminalization of slave-owners, tax-cheats, cigarette companies, nazi, apartheiders etc.

Deaths happen in road accidents for many reasons. Following is 2018 report on Yamuna expressway to agra (HT may 25, delhi). Sleep drivers = 45%. Drinking = 14%. Speeding = 19%. Traffic rules violations = 11% Mechanical 11%. Aaquantum style human = 90%, mechanical 10% (tyre burst, bad mechanics, damaged warning, highway layout,…). Sleepy drivers, speeding, violators and drunk are easy to fix and catch, difficult to enforce. Mechanical are difficult to catch, easy to fix but are only 10 % of total. They also are 90% of intellectual conversations. This is a simple example from many of why I consider intellectuals pointless! That is 90% of class-of-75 !!!!!!!!!!!!!!!!!!

Everyone has unique risk factors and causes of demise. Risks do not add as they come with inner correlation. Risks are divide-able into fixed and fixable. Factors like age, sex, genetics etc. are fixed.
Fixable (me) are divisible into two – measurable and statistical. There are varying costs, pain and error rates of measures. The proper investigation method is Very subjective and experience+SKILL dependent with inverted-U (quality vs. experience). Perfect for AI robot or my current mehod od scepticism unless confirmed by sens or Cochrane collaboration (not even mm doctors say so) or journals sceptically, only if peer reviewed.

These methods work for diabetes treatment as death analysis as buying-decisions and indicate an underlying epistemology certainly shared as it evolves.


Thursday, May 24, 2018

Inside of a nucleus



Following story had an electric effect on me – it tells of real problems in working with quantum computers, likely to become common-place by 2030, and the basics of what quantum computers can and cannot do, for realistic reasons, not perfect QC capabilities!


1.       QC are programmed by comparing answers against tractable normal cases in boundary condition
2.       That match requires deep analysis of noise, artificially added and slowly removed. Unsaid but obvious is that a fixed point algorithm was used. Noise add to some problem can be, while others cannot be removed so.

3.       Generalization of boundary problems is assumed to work. This might be true – say deuterium to tritium etc., but may or may not in heterogeneous systems.
4.       The problem of latency between the users and cloud-based services is severe. Latency and crytion-trust are two fundamental limitations of cloud computing. One can drastically reduce internet latency by in-house QC for example.

5.       Real world programmers will likely not be motivated as these scientists.

Tuesday, May 22, 2018

Strange moons of Saturn




Just look at them, how come so weird!

Martin Jutzi and Adrien Leleu, both members of the NCCR PlanetS, took the challenge of calculating the formation process of the small inner moons of Saturn. The first, simple tests worked well. "But then, we took the tidal forces into consideration and the problems piled up," remembers Adrien Leleu. "The conditions close to Saturn are very special," confirms Martin Jutzi. Since Saturn has 95 times more mass than Earth and the inner moons orbit the planet at a distance of less than half the distance between Earth and Moon, the tides are enormous and pull almost everything apart. Therefore, Saturn's inner moons couldn't have formed with these peculiar shapes by gradual accretion of material around a single core. An alternative model called pyramidal regime suggests that these moons were formed by a series of mergers of similar sized little moonlets.

Read more at: https://phys.org/news/2018-05-history-saturn-small-moons.html#jCp


Take away is that sometimes astronomical bodies are formed by merger in special situations (Saturn tides).

Graceful aging: aaquantum scholarly research




What are prospects of fountain of youth in near future?


Yes, Sinclair told his audience, “We can turn an old mouse into a healthy young mouse.”

The Fountain of Rodent Youth feat, outlined in March in the scientific journal Cell, hasn’t been replicated with humans. But researchers, who have long scoffed at the anti-aging claims made by companies pitching dubious products, are warming to the idea that serious science can be deployed to increase human longevity.

Ambitious efforts are underway in Massachusetts and beyond to develop the first government-approved drugs to stretch healthy life spans. Some researchers are scrambling to repurpose a diabetes medicine to target age-related diseases. Others are working to boost levels of a key protein to increase blood flow and endurance, or to find a way to kill “zombie cells” that can send out toxins that cause age-related maladies.

Arun aaquantum notes
repurpose a diabetes medicine
metformin. Remember latest research says insulin, very useful to 35 turns bad after 45! Most current mm doc were taught wrong!

How long can humans live – some feel not very long!

In the 1960s, Hayflick found that human cells divide only 40 to 60 times, after which they stop — even when their division is paused and then allowed to resume. This discovery, called the Hayflick Limit, indicates that even if a drug like metformin were effective at suspending aging, the end game stays the same.

Shouldn’t someone, likely to die, be allowed treatment wished?
So say conservatives and Trump and US just passed a bill. But it is’nt a simple issue! Other side has good arguments. It is similar to suicide by suffering hopeless terminally ill!

Isn’t aging alleviation in near future by crispr driven gene therapies?

There is no question that if scientists aren’t careful, CRISPR can induce substantial off-target mutations. In another study Joung’s lab submitted to a journal, they show that when “promiscuous” forms of CRISPR were slipped into mice’s livers, as some genome-editing companies hope to do for some human metabolic diseases, it edited hundreds of spots in the mouse genome that it wasn’t supposed to.

by crispr driven gene therapies?

Elementary CS has the answer as I learned in 1976 studying L_systems. Lindenmeyer systems are parallel context sensitive grammars made type-2 by passage of time which can be viewed in onary notation. Problem is simple – crispr allows one to edit-replace sequence of letters of genetic code say CATG to CCAT by changing CAT to CCA, but it does it everywhere even unintended. Not simple but progress made.


Arun aaquantum view
even if a drug like metformin were effective at suspending aging, the end game stays the same
True but error is in assuming that there is no stem cell! Tree cells have shown the way past - a stem cell also divides and the stronger cell lives! That is what transfection does!! I, Arya aaquantum, am still very hopeful of transfection driven anti-aging.

Explored and used interventions?

Metformin
supplementation of three subcycles of krebs cycle
Preventative supplements for gross body objects

Explored, india has advantages

low labor cost
posses real estate
simple operation

Hence 2 week to 2 month medical tourism makes sense - I provide equipment, operator, living, food from dedicated chef - full tour package, turn key basis

Meaningful aging interventions

The three procedures referenced next are
- uniquely addable by me as a non-doctor for upper middle class
- Have existing documented benefits
- Unlikely to have negative effects. Worst is mild benefits!
Thus flooring lazy nincompoops.

- ECP External counterpulsation used to escape stent surgery. My add is reducing costs to enable upper middle class.

- HOT Hyperbaric oxygen therapy - Mayo Clinic commonly used by aging film stars. My add is reducing costs to enable upper middle class.

- Human Parabiosis - Wikipedia but legally - Doable by upper middle class.


Collectively, the mechanisms are disjoint - improved blood flow through angiogenesis, high pressure yoga-like and stem cells. Doing all three should benefit me visibly and empirically documentable. 99.99 readers will view it skeptically and move on! Tough luck!

aaquantum scholarly research


This page is intended to be the end-product of evolutionary developments, imagined to be very substantial but not even penned yet. To be a scientist means to me to be rational skeptic

First requirement is integrity and it will happen as soon as my IBE is done.

Next is skeptic nature of enquiry into decompositions. The whole may be an AND of components or an OR or a NOT. If an OR, single failure does not demolish the theory. Skeptic enquiry may sharpen the region of applicability.  Second order paradoxes are removed without eliminating recursion by requiring that all dependents range over previously defined elements only! Goedel is automatically eliminated - consistency and completeness of a language can not be constructed within! In other words (all x)F and (exist x)F are illegal, one must say (all x in X)F and (exist x in X)F where X are predefined! I call it aaquantum typed logic.

By goal, completeness in not an objective or perhaps even possible. Nor is full consistency - a mechanical way to test arbitrary derivations as being consistent. However, one can define consistency as those sentences derived by consistent applications of consistent axioms. Similarly complete. Skeptical enquiry is required for all statements independent of accepted sets.

This pragmatic outline suffices to constrain my behavior to an aaquantum stoic, free from all known paradoxes, unconstrained but rationally accepting stoic, pragmatic to live, with limited shared effort. The tools are finally here - internet, IBE, middle class comfort. Fuck the legal stupids, entirely new ideology can be constructed, as subset of current law till the end. The goal is simple enough - an aaquantum-stoic can not be cheated - politically, seller, friend, colleague, law etc!

aaquantum means discussed evolution, enforcement without appeal to good nature, responsible crime abatement etc. Different laws of 'guilty unless proved innocent' apply to specified minority: repeat offenders, celebrities and inspectors where honey traps can be officially used.

First interstellar immigrant discovered in the solar system – aaquantum research summary



Q. How can one say, within aaquantum-epistemology, that a discovered denizen of our soloar system was captured from another star?

A. We turn to the formation of solar system! It grew from a rotating formation cloud in which gravity constructed various planets at various distances all rotating in the same plane in the same direction, while the centre grew in mass, started fusion, and became the sun. Prior to the formation of planets, a nearby super nova has seeded the cloud with some post-iron elements.

Empirics?

All the planets are measured in same plane, rotating in the same direction.

The oort cloud?

Elements past Neptune were too far away and could feel gravity of near by stars. They collected as a sphere of icy bodies with very elongated tracks in noparticular plane. We know them as comets!
Retrograde motion?

Some bodies near jupitor in the asteroid belt do not spin like planets in plane and same direction.6500 do but 100 do not! They are interesting objects! Most are lkly captures from the oort cloud by Sir Jupiter, itself a failed star!

Extra-solar?

One retrograde guy is special. Its orbit was computed in detail, enough precisely that one could project it back 4 billion years. It stayed true that long! It could not come from oort cloud, it could not have condensed. That, as Sherlock would say, leaves only capture from nearby star. A plausible low probability story.



Proton innards

Monday, May 21, 2018

THE epistemological problem – aaquantum scholarly research

John Locke

The epistemological  problem is simple i.e. who to believe. It is central to a human. Their many ways are conflicting and cannot coexist. What I have wanted is low cost & effort unhackable way to yield a 67%(2/3) or better solution always!

The following are subhuman ejects anyway (reasons NOT discusses, what follows is POINTLESS for those wh0o so believe) – religion, used car salesmen, doctors, friends, politicians, lawyers etc. The people I address are sceptics who wish to understand and when & what is rational. Unlike a true skeptic, further investigations are NOT done somehow and claims casting doubts are rejected as well. There is close connection between my goals and best of law, except that there is no constitution and historical evolution.

Unhackability is very crucial but avoided entirely here since zillions times better than best human systems can be constructed using IBE encryption extended aaquantum. Many legal practices are quaint zillions of times worse, only existing since an aaquantum ideology has not established a superior state. We posit (as elsewhere) that aqaquantum authorities exist answerable and accountable to many more aaquantum authorities, and that their decisions can reach me without hacking.
First observation is that epistemological needs can be divided in most cases into mutually non-conflicting categories easily by a target (of my work) and in conflicting cases, the aaquantum-decision can be safely followed. So the aaquantum-epistemology can be a construction over many subject-epistemologies. Evolution is my choice in development of aaquantum epistemology. Detection of a fatal flaw in one sub-epistemology does not render most other parts inoperative. Goedelean work shows that fatal flaws CAN be found system-wide. Given that no one as Goedel existed for 3000 years and that no one as him has reappeared since his work about century ago, it is reasonable to argue that my work will live thousands of years – freedom from Goedel, scepticism of another Goedel, safe evolution.

Each of my epistemology follows this pattern – decide on own based on general principles, ask when not clear (unhackable internet, perhaps a conversation). It clearly was not possible before 2000 (internet, IBE) and hence any moron who argues for aspects in Qing dynasty is an idiot without wasting more time. How many distinct ideologies have grown after 2000? Isn’t aaquantum special if it coheres? Conflict with any other ideology is irrelevant as long as it is coherent. What is MORE important is practical completeness – 90% of ALL questions and 90% of all important ones, in 90% of endeavour!

So what is scholarly research? An essay where all important transitions are either simple to understand, or html pointers to relevant research or paper. I speak much on some topics of interest to me – quantum mechanics, astronomy, cosmogony, aging, development of diseases, identity encryption, identity, unhackability, secure sharing, evolve-able software. None of my targets need to understand details but they can if so interested. My critics can attack me or references. Above is not referenced as I think my targets know my mastery in unhackability and know evolution and Goedel




TBD = To Be Done


TBD quantum mechanics – scholarly aaquantum research

TBD astronomy – scholarly aaquantum research
TBD aging – scholarly aaquantum research
TBD development of diseases – scholarly aaquantum research
TBD identity encryption – scholarly aaquantum research
TBD identity – scholarly aaquantum research
TBD unhackability – scholarly aaquantum research
TBD secure sharing – scholarly aaquantum research
TBD evolve-able software – scholarly aaquantum research

Friday, May 11, 2018

Towards my first patent application – aaquantum scholarly research

f

Goal is to research devnagri fontCode and patent it. What is roman fontCode? Embedding imperceptible information in documents by unconscious perturbations in font used for printing. A book has random changes any way due to imperfections of press. Restricting deliberate changes to selected positions makes the code impossible to detect since codes can be misbroken so that any message can be found in any book!


The idea of other languages has occurred to the authors but in reality they are likely weak competitors! Perhaps colleagues here can suggest bell and whistles, or newer uses. The list of
Applications outside spycraft in paper is very small! In fact, I can even think of applications in honey-trap of students mis-doing their assignments by putting questions on internet for bids!

Morning diabetic sugar high: scholarly aaquantum research


Given in my epistemology

1 100% non-scholar non-mm-doctor and 90% of mm doctors are idiots
2 only normal people are cochrane collaboration, SENS, MIT biology and scholars

view my research with care or move on.


Clinical Question

Does metformin increase the risk of fatal or nonfatal lactic acidosis?

Evidence-Based Answer

In patients without standard contraindications to metformin therapy, metformin does not increase the risk of lactic acidosis.1 (Strength of Recommendation = B, based on inconsistent or limited-quality patient-oriented evidence)

Blood Sugar Chart

Updated March 27, 2018
 Print Text Size: A A A
This blood sugar chart shows normal blood glucose levels before and after meals and recommended HbA1c levels for people with and without diabetes.
BLOOD SUGAR CHART
Fasting
Normal for person without diabetes
70–99 mg/dl (3.9–5.5 mmol/L)
Official ADA recommendation for someone with diabetes
80–130 mg/dl (4.4–7.2 mmol/L)
2 hours after meals
Normal for person without diabetes
Less than 140 mg/dl (7.8 mmol/L)
Official ADA recommendation for someone with diabetes
Less than 180 mg/dl (10.0 mmol/L)
HbA1c
Normal for person without diabetes
Less than 5.7%
Official ADA recommendation for someone with diabetes
Less than 7.0%

A Bedtime Snack and Blood Sugar: Diabetes Questions & Answers
Published April 12, 2018 by Gary Scheiner, MS, CDE
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Q: Does a bedtime snack help or hurt the wake-up blood sugar reading?
A: Like most things having to do with diabetes, it depends. If you are not taking insulin, bedtime snacks can either cause your wake-up reading to be elevated or force your pancreas to produce extra insulin during the night to offset the effects of the snack — neither of which is a good thing.
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If you take insulin, a bedtime snack may be needed if your blood sugar tends to drop overnight. This is often a sign that your basal insulin dose (via injection or a pump) is a bit too high. Basal insulin’s job is to keep your blood sugar steady overnight. So if you’re dropping, you may be getting too much basal insulin. In this case, without a snack, you might wind up with low blood sugar in the middle of the night. And if you overeat or “rebound” from the low, your wake-up reading could wind up too high. So with basal insulin doses that are a bit too high, a snack at night may be necessary. However, it would be better to get the basal insulin dose set properly.
If your basal insulin dose is correct and your blood sugar holds steady through the night without a snack, a bedtime snack will make your blood sugar rise. A dose of rapid-acting insulin would likely be needed to offset the effects of the carbohydrates in the snack.
While we sleep, the body produces a hormone called leptin that curbs appetite. So if you’re trying to shed some body fat, a bedtime snack may be counterproductive. And since excess body fat leads to insulin resistance, all those extra bedtime snacks can lead to higher-than-desired blood sugars in the morning that persist around the clock.
Want to learn more about maintaining target blood sugar levels during sleep? Read “Exorcising the Specter of Overnight Hypoglycemia” and “The Dawn Phenomenon and Somogyi Effect: What You Can Do.”
Gary Scheiner, MS, CDE, is owner and clinical director of Integrated Diabetes Services (www.integrateddiabetes.com, 610-642-6055), a private practice specializing in intensive insulin therapy for children and adults. He and his team of certified diabetes educators work with clients throughout the world via phone and online. Gary has lived with Type 1 diabetes for 30 years and was named Diabetes Educator of the Year in 2014 by the American Association of Diabetes Educators. He has written six books, including Think Like a Pancreas, and is a regular contributor to Diabetes Self-Management.
Disclaimer Statements: Statements and opinions expressed on this Web site are those of the authors and not necessarily those of the publishers or advertisers. The information provided on this Web site should not be construed as medical instruction. Consult appropriate health-care professionals before taking action based on this information.
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The Dawn Phenomenon and Somogyi Effect: What You Can Do
https://www.diabetesselfmanagement.com/blog/dawn-phenomenon-somogyi-effect-can/Published October 23, 2017 by Amy Campbell, MS, RD, LDN, CDE
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Waking up with a high blood sugar reading is not exactly the way you want to start off your day. Besides rushing to get ready for work or getting the kids off to school (or both), you now have to decide if and how you’ll deal with that reading on your meter. Maybe you decide to skip breakfast. If you take mealtime insulin, perhaps you inject a few extra units. Or you put in some additional time during your workout. Another option is to shrug it off and hope that your blood sugar comes down in a few hours. You might also ponder the reason your blood sugar is high. Could it be that you ate dinner later than usual last night? Or you ate too much carb at dinner? Or maybe it was your snack?
While it’s normal to have high blood sugars when you have diabetes, it’s time to pay attention when the highs become the norm. Morning hyperglycemia (high blood sugar) is frustrating for many people; figuring out the cause is the first step in dealing with (and preventing) it.
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Dawn phenomenon: hormones that wreak havoc
It’s easy to blame your morning high on the plate of pasta last night. But while that could certainly be a factor, chances are, your “highs” are a result of hormones. An imbalance of insulin, amylin (a hormone released by the pancreas), and incretins (hormones released by the gut) is the likely culprit. Other hormones get in on the act, too, including glucagon, growth hormone, cortisol, and adrenaline. Why? Overnight, the body gets this idea that it needs fuel (glucose). The witching hour seems to be around 3 AM or so. At this time, the liver and muscles obligingly respond to the signal for fuel and release glucose into the bloodstream. In someone without diabetes, insulin and its other hormone pals kick in to keep blood sugar levels on an even keel. In the case of diabetes, though, those hormones are pretty much missing in action. End result? Blood sugar levels climb. You wake up, check your blood sugar, and it’s above and beyond the “80–130” range. In case you’re wondering, this cascade of events is called the “dawn phenomenon” or “dawn effect.” It’s estimated that between 10–50% of people with either Type 1 or Type 2 diabetes will experience this at one time or another.
What you can do about the dawn phenomenon
• First, figure out what’s happening overnight. This means, for a few days in a row, setting your alarm for around 3 AM and checking your blood sugar, and then checking again when you wake up at your usual time in the morning. If your blood sugar is within your target range when you check at around 3 AM but is high when you wake up, there’s a high likelihood of the dawn phenomenon going on.
• Rethink your bedtime snack. Some experts recommend avoiding carbohydrate close to bedtime. If you can’t squelch those hunger pangs, try eating a low- or no-carb snack, such as a small handful of nuts, a hard-boiled egg, or raw veggies dipped into nut butter that doesn’t contain sugar. On the other hand, other experts recommend eating about 15–20 grams of carb — doing so may prevent the liver from pumping out too much glucose. Examples include a small piece of fruit, 6 ounces of light-style yogurt, or 3 cups of popcorn. Try out both options and see if either one helps to lower your fasting blood sugar.
• Rethink your diabetes medicine. This can mean changing the time when you take your medicine, whether it’s a diabetes pill or bedtime insulin (meaning, take it at bedtime rather than at dinnertime). You might also benefit from changing the type of medication that you take, or even adding a medication, such as a long-acting insulin. Talk with your health-care provider before you make changes to your medication schedule, and discuss any other options that may be available.
• Consider an insulin pump. If you have Type 1 diabetes or Type 2 diabetes and take both fast and long-acting insulin, using an insulin pump can help you better manage your blood sugars overnight and into the wee hours of the morning.
Somogyi effect: rebounding from a low
The Somogyi effect, also called the rebound effect, is named after Michael Somogyi, a Hungarian researcher who first identified it. The claim behind this effect is that the blood sugar goes low overnight. This drop triggers the release of counterregulatory hormones, such as adrenaline, cortisol, growth hormone, and glucagon, which, in turn, signal the liver to release glucose. The result? Blood sugars rebound and are higher than desired in the morning. The theory, too, is that those hormones create insulin resistance, so that it’s sometimes harder to lower those morning readings.
Interestingly, scientists question the Somogyi effect; some studies have failed to prove its existence. Other studies, however, have shown that this occurrence happens in those with Type 1 diabetes.
What you can do about the Somogyi effect
• If you’re curious about the Somogyi effect and think it could be happening to you, once again, you’ll need to wake up during the night to test it out. A low blood sugar at around 3 AM followed by a high blood sugar when you rise and shine could prove this theory to be correct. You might also have the following symptoms: a rapid heart rate, night sweats, a headache, blurred vision, thirst, and/or dizziness.
• Using a continuous glucose monitor (CGM) is another helpful way to get a picture of what your blood sugars are doing overnight. A CGM checks glucose levels about every five minutes, and also will alert you to either high or low glucose levels, using an alarm.
• The best way to stop the Somogyi effect in its tracks is to prevent it in the first place. This means adjusting nighttime diabetes medication (either your sulfonylurea or your long-acting insulin), making sure you eat enough in the evening (no skipping meals), limiting alcohol intake, and planning for exercise more carefully. Talk with your diabetes educator or health-care provider about options that are best for you.
Morning high blood sugar: more food for thought
• Sure, it’s a pain to have to wake up in the middle of the night to check your blood sugar. Remember, though, that this isn’t forever. If you can do this for at least three nights, you should get a clearer picture of what’s happening. Pick nights when you feel well (meaning, you don’t have a cold or the flu), you aren’t planning to exercise between dinner and bedtime, and your bedtime blood sugar is around 150 or so (not too high, but not too low, either).
• Experiment a little with bedtime snacks, as mentioned above. You may find that not eating a snack helps with your morning blood sugar; on the other hand, eating a reasonable carb-containing snack may help, too.
• Pay attention to high-fat dinners and how they may affect your morning readings. Fat doesn’t directly affect blood sugars, but it can increase insulin resistance and also slow the digestion of carbohydrate. This means that four, six, or eight hours later, you’ll see the effect of that fatty meal on your blood sugars. There’s also some evidence that saturated fat can increase or worsen insulin resistance, as well.
• Don’t overlook the role of stress on your diabetes control, too; recent or extreme stress, whether it be issues at work or at home, an illness, or a recent medical procedure, for example — can affect your blood sugars.
• If you have Type 2 diabetes and you continue to wake up with high readings, don’t be afraid to consider starting, switching, or adding medication, including long-acting insulin, especially if lifestyle changes, such as weight lossphysical activity, and meal planning, aren’t enough to get and keep your blood sugars in a healthy range.
Want to learn more about the dawn phenomenon and Somogyi effect? Read “Controlling the Dawn Phenomenon” and “Somogyi Effect.”
Disclaimer of Medical Advice: You understand that the blog posts and comments to such blog posts (whether posted by us, our agents or bloggers, or by users) do not constitute medical advice or recommendation of any kind, and you should not rely on any information contained in such posts or comments to replace consultations with your qualified health care professionals to meet your individual needs. The opinions and other information contained in the blog posts and comments do not reflect the opinions or positions of the Site Proprietor.