Sunday, February 11, 2018

For a life well lived


For a life well lived

I am a nobody now, but fully charged optimistic with several relevant interesting world-improving avenues open. I need to address aging, wealth, religion, friends, politics and personal impact. You must too, peruse quickly through for how and must commit to paper. My experience indicates publicizing may benefit someone, someone may help remove bugs, sharpen thinking by doubts, forces discipline and acts as invisible hand!

There are at least four major new ideas developed by me, speculated after my intense internet searches! These are Everett-like interpretation of Quantum mechanics; CCC-like genesis; blockmediumdecentralization; and missing-reactants theory of aging.

Personal impact

It is crucial for I can understand death now as beyond something that happens to others only. I do envisage, define and implement a formal language aalan, which address three new problems – non-determinism like vastly improved yacc; blockmedium, a simplified private blockchain like vastly improved bitcoin; and abandoned greatly different software from efficient multiple inheritance despite c++, being the way all intelligent human think, hence robots.

“In god we trust, all others need data”, says my IITK senior brother-in-law hobnobbing with USA generals! This is a great essay but where is the meat? First an answer, then time bound implementation. Deadline March 20, 1918.

A professor never retires or becomes ancient. Nor does an essay writer, author etc. Just to stay relevant, you have to interact with the world. The world changes again and again, but you must explain to yourself why the change – shortcomings of the past, how fixed in new world and then two kinds of research – relevance and logical conclusion of the new existing – tech fi; and relevance and impact of newer subjects needing to open up – sci fi.

There is so much scope for tech fi. Blockchain and blockmedium have opened up to non-heretical administration and truly distributed systems. These systems are impossible to defeat – a part escapes disaster and regrows like hydra.

Sci fi inventions must understand no go theorems and around them! Classic is big crunch that cannot happen in classic universe but can in quantum universe. FTL is prevented by no go of any material travelling faster than light but nothing prevents the space-time (and its contents) forming an FTL bubble (delivering its cargo FTL)!

Religion

Prior to adopting one (absolutely irrelevant is my inheritance), I must adopt an epistemology – belief process and what/why do I believe in! By definition, it immediately  means empirical. So a young Vivekananda asked his guru – “have you seen God?” “yes, I have and show him to you”. Unreported is how much education would be needed! I suspect after a few years, the swami actually saw God! Lesson is care need to use in questioning Indian guru! Dawkins was easily trapped by senior religionists early. But he learned. Experienced Dawkins slays opponents of evolution at ease!
If one is NOT doing to believe accomplished thugs of Indian religion, then what? Only reality is death. What about the evolution of the Universe? Of life? Surely God-of-the-gaps is real, we know some things, all the others God does! A very clockwork universe where “the moving finger writes” and one can create logically consistent explanations of all probabilistic things, that are guaranteed to be untestable! Rather than waste time understanding these, it seems better to understand hard but testable explanations. So my three interests – astronomy for Universe and birth;  biology for aging and Life; and quantum physics for Nano materials and new communication.

And stoicism is it, one of major godless religion like Buddhism, dead for 2000 years but being revived, the religion of scientists even when they disclaim all religions – they are still nice and accept social order. In 2018, one can explain creation, elements and astronomical universe, unfold the physics of life, speculate on big bang and black boles, play with enormous energies at VLC, empirically test neutrinos, work on magic Nano-materials, imagine what is possible etc. But my serious immersion in astronomy, biology and quantum physics is not an understanding dead end.
This brings me to the neologism by me – pregnant-science. By definition, it is like religion in that no existing tests exist that prove or disprove, such tests are eventually possible and these speculations derive today sciences. In my term, they are ready to give birth to new sciences whenever.

Idea 1: aa-interpretation of Quantum Mechanics by pregnant-science

Motivations is parsimonious Everett’s many worlds. This theory holds that QM is not strange at all! Every quantum experiment is normal and deterministic in the world which experimenter is in . The number of Everett universes is astounding like 1000 ^ 1000 ^ 1000, but it works! Classic interpretation was from Bohr with mysterious mind-boggling idea of collapse at the precise measurement moment – it was a probability wave when not watched. Further, some intelligence was required in the observer. “How did the universe evolve before intelligent observers?” was a hard question! Between 2005 and 2015, the number of professional quantum physicist believing Bohr dropped form 40% to 5%. Everett believers went from 10% to 45%
Around 2014-2016, people were forced to calculate wave functions of molecule electrons. It is VERY hard for single multi-electron element. This is Quantum chemistry! It was done by some clever approximations. When the approximations were examined, they were as if multiple Everett’s word were coincident! Perhaps they were not all independent!
Giving deep thought to this problem, I decided that there was only one universe, but time was 2 dimensional, with the extra dimension to be quantum sized, hence too small to be noticed in macro time, but important in quantum objects! So was born aa-interpretation. Experiments with quantum hall effect indicate an extra spatial dimension. Hence a six dimensional universe, independent of string theory, each a conclusion from a pregnant science.

Idea 2: AACCC cosmogony

What caused the big bang? It is addressed by many theories in pregnant-science of Cosmogony. There are six important alternatives! This is NOT about big bang cosmology. There are proof in CMB for it to make sense (any other must explain evolution of quantum dots in CMB to galaxies and spectral lines in CMB).

One I love is the CCC alternative of Sir Penrose. Inverse of big bang is big crunch. Perhaps the universe is in editions. Each edition is created in big bang and dies in big crunch. All but the last which expands for ever. CCC requires no big crunch but a universe ends in mysterious mathematics after infinite expansion! But I work later to Sir Penrose! My AACCC has two extra things

1.       LQG cosmology has posited a maximum crunch capacity of space. Things never crunch down to singularity but maximum density after which explosion occurs. No new physics is needed at some singularity.

2.       Big crunch is possible despite 2nd law of thermodynamics.

It is a pregnant science because it is possible for an edition to leave empirical effects on next! These are circles in CMB from collision of really large black holes in previous edition! Have they been seen in our CMB? Controversial – some see them, others do not and dismiss it as psychological effects in perusing random noise!

Personally, AACCC is a pregnant science, not science yet! Even if a science, perhaps there are other incompatible cosmological theories so predicting!

Cosmology: It is study of evidence in this universe and use that to empirically choose. One controversy is about dark matter and dark energy. Dark energy is simply that of quantum vacuum. Dark matter may not exist! Verlinde gets MOND by treating gravity as an emergent entropic force, reduces to standard newton inverse square law but not when gravity is weak.

Universe is consistent with big bang 13.7 billion years ago. Also with infinite past with quantum meridians!

Idea 3: Missing-reactant theory of Aging


Aging is a disease. Right way to address it is SENS like positioning between gerontology and geriatrics to focus on repair. Aging is life-long accumulation of damage to DNA which reduces some chemicals required as cofactors in Krebs cycle. This is the set of reactants in mitochondria of every cell in every life! That is how I know I am right! Mouse studies can be carried out to test conclusions of mine and SENS.

Vitality and Longevity are two possibly conflicting goals, in my case vitality is more important. Diet-restriction increases longevity at price of vitality. So only mild restrictions are practised in random pattern less fashion.

So Aging is accumulated damage to DNA resident in cells. Strategies to alleviate consequences are

1.       Replace the missing cofactors
2.       Manipulate DNA as per SENS
3.       Replace entire DNA
4.       Some combination of above


I recommend 4. Here are considerations

1.       Replacing missing reactants requires the chemicals to be known and reach mitochondria of every cell. That requires, in general, escape from environmental stresses, penetration of stomach, penetration of cell wall and mixing into mitochondria parts. Each barrier reduces by a factor. Stomach barrier impact can be reduced by Ayurveda concoctions and increased (sugar in diabetes) by acarbose. Injection, directly into blood is one approach.
The Krebs cycle can be approximated by 3 – ATP, NADH and Citric acid. They are all benefitted by anti-oxidants since reactive oxygen in all cases hurts the cycles. Three ingredients are ATP by Coq10+Shilajit, NADH by NR/NMN, and citric remnant by Lipoic acid.

2.       Manipulate DNA as per SENS. This is a strict medical topic. To watch and judge.

3.       Replace cell! This is normal part of all organisms. The division and replacement seems to be species specific with telomere forming important counters for us. Division is by DNA helix forming a pair by uncoiling and recoiling. Problem is that damage is transmitted in copy as well. Better approach is if a stem cell is present during the division and it competes with the diseased duplicate. This happens in transfection delivery of programmed skin cells. It started August 2017 and is too early to base any predictions except tech fi! To watch and judge.

So my strategy is to watch and judge. Only 1 is adopted, which means nr, cq10, Shilajit, lipoic acid supplementation and not vitamin C, vitamin B3, resveratrol, glutathione etc. supplements! This is a very dangerous area, with extreme care needed.

Epistemology – vitality before longevity. Trust no one, including doctors (too many prescribed insulin increase!). Leave something to SENS and Cochrane collaboration. Filter supplements by Krebs cycles and barrier penetration. Only cost prevents mito4 supplement but coq10 & Shilajit.



Idea 4: Blockmedium decentralization

Blocmedium is contention-free blockchain. It can be used for crowd-funding. But there are many dangers like ICO.
TBD

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