This text follows this link (https://aaqg-arunarya.blogspot.com/2022/12/arya-theory-of-aging-dr-arya-theory-of.html), essential read once to understand what follows.
How did life arise?
The two important concepts are cell and evolution. Everything life follows from it - cells form bacteria, plants, animals, and humans. Over time, evolution selects, prunes, and enriches populations. Individuals hate death but evolution cares not, like nature. It is a simple word describing part of nature. For linguistic reasons, humans attribute purposeful behavior to it. If you fail to understand life as evolution, you are a moron, and this account is not for you.
So what is the history of life?
Somehow the chemical soup on earth a billion years ago produced DNA that could repair itself by the exclusion of repair and replication. The cell in which DNA could exclusive-or could survive and rebreed many times than all other cells without DNA. Evolution was on. Survivors of punctuated natural selection became all life on earth. Some life evolved much faster with sexual reproduction. Life became mobile with the rise of animals. Animals needed food from plant life and other animals. This led to a dinosaur planet.
Last 63 million years?
A huge asteroid hit the earth, disrupted life, and wiped out dinosaurs and large animals, Only survivors were small mammals. Worldwide, period samples demonstrate thin separators. The small mammals evolved into modern animals. Some animals evolved much faster due to a small life span from genetically programmed old age. Unlike the top of the food chain program-free non-old-age animals, they died 10-20 times faster but still succumbed to cancer like top animals.
Old age saps the will to live and opens the person to a plethora of diseases. Only since 2005 (parabiosis experiment) has even the thought of defeating old age become meaningful. I became aware of the scientific curiosity of no old age from friends at MIT in 2000, from a British doctor. Just 22 years later, I have successfully intervened in myself. It is not cosmetic but bodily as not only do I look 50, my body feels younger and I have regained sexual performance.
I am not a doctor and do not follow them unless I prune them based on mechanism. This note documents the method I use. I may be wrong, what matters is benefits and timely termination of hurtful.
The Goal?
Reduce old age infirmities and strengthen me to exercise. On the return of Dad from the USA in 1960, he brought two books among others of Lalane on exercise and Gamow's "One Two Three ...". The latter gave me lifelong respect for physicists and astronomers. The former is on health, exercise, old age, and diet, man lived to be 95, and died in 2011, the only American I never knew but felt sad about passing. When I turned 60, reviewed myself. The only reason for less exercise was tiresomeness which had a positive reinforcement loop as old age causes less exercise! So old age control by medicines has allowed me to exercise! Tiresomeness has reduced! The goal is not money or fame but documentation for critics to tear into me and force me into improvement!
Unified mechanism?
Evolution made humans, it is about the survival of the fittest. For hundreds of thousands of years, human ancestors survived the situations of real life, cold, excess heat, hunger, famine, disease, tiredness, man-eaters, enemies, etc. Not all survived. The populations that survived had in-built protections from these ravages, part of better survival of the filter. Human technology of consequence is a few thousand years old, too small on evolution scales. That means we will still act like our ancestors to artificially created evolutionary scenarios. Not surprisingly, we have enzymes that are activated in adversity-mimetic situations. Such scenarios are one way to fight old age by activating defensive scenarios.
Hormesis?
This means "what does not kill you, makes you stronger". Hunger means fasting but not avoiding needed chemicals. Sounds deep but is not for now what is needed. However, to someone who knows, it makes an easy explanation. I have invented a term for it, asymmetric understanding. It is when a solution is known hard but checking a solution is trivial.
Why not borrow from other life their fight response chemicals?
Exactly. It is called xenohormesis or compatible foreign life hormesis. The best are chemicals in edible plants or known medicinal plants. The case is resveratrol or cousins, used by plants to fight infection but known compatible with humans. All plants we eat make their chemicals for some ancestral purpose and happen to meet our needs too. In general, edible colored plants have useful fighters.
Composition of work of doctors?
consider the difficulties
1. Funding for studies makes the point that inadvertently the researcher will sing what the employer or funder wants.
2. Every expert has a built-in ego to claim its method is really how aging works. The proof is age-gain but no proven age-reset.
3. Seller will suppress cons and advance pros.
4. The Supplement market is full of fake chemicals.
Simple no hypocrisy means I may be wrong, unlikely as not costing money and not funded and claiming to have no reason. I do it for acknowledged support for the USA SS in my TBI, hoping that the need will vanish some day in my life. Law provides for that.